“…Furthermore, adding mirtazapine to the SSRIs treatment, the patient reported a dramatic decrease in nausea, insomnia and appetite loss without any neonatal complication in the baby (Uguz, 2013). With regard to tricyclic antidepressants (TCAs), PD patients treated with nortryptiline (Nascimento et al, 2004) and imipramine (Uguz et al, 2014;Ware and DeVane, 1990) benefited from pharmacotherapy, reporting remission of panic symptoms. In the largest clinical sample to date, based on the Clinical Global Impression-Improvement Scale (CGI-I), 75% of pregnant women responded to low doses of imipramine (10-40 mg/day) with a statistically significant reduction of the mean number of panic attacks per week from 12.9 to 2.7 before and after the treatment, respectively (Uguz et al, 2014) (Table 2).…”