2002
DOI: 10.1016/s0735-1097(02)02479-8
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Transthoracic Doppler assessment of coronary flow velocity reserve in children with Kawasaki disease

Abstract: The CFVR measured by TTDE predicts the presence of significant coronary stenosis of either the right coronary artery or LAD, as well as myocardial ischemia of these territories in children with KD.

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Cited by 32 publications
(18 citation statements)
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“…Transthoracic Doppler assessment of coronary flow velocity reserve in the posterior descending and left anterior descending artery predicted the presence of significant coronary stenosis of either right or left coronary artery. These data correlated with perfusion defects on Tl-201 SPECT [13]. An echocardiographic image of aneurysmatic left coronary artery is presented in Fig.…”
supporting
confidence: 64%
“…Transthoracic Doppler assessment of coronary flow velocity reserve in the posterior descending and left anterior descending artery predicted the presence of significant coronary stenosis of either right or left coronary artery. These data correlated with perfusion defects on Tl-201 SPECT [13]. An echocardiographic image of aneurysmatic left coronary artery is presented in Fig.…”
supporting
confidence: 64%
“…Normal values for Doppler flow velocities in the left coronary artery are reported in a number of children and are also studied in the branch arteries. Peak flow velocities during diastole range up to 60 cm/s in young children and decrease with age and increase with heart rate [124][125][126][127][128]. Coronary flow reserve (CFR) reflects the increase in coronary flow in response to hyperemia by adenosine triphosphate, dipyridamole, and exercise.…”
Section: Coronary Arterymentioning
confidence: 99%
“…CFR reflects the resistance of the coronary bed, its autoregulatory ability, and the ability to augment blood flow in response to stress. CFR is affected by stenosis of the proximal coronary arteries in Kawasaki disease [125] or by abnormalities in the coronary microcirculation in dilated cardiomyopathy [129].…”
Section: Coronary Arterymentioning
confidence: 99%
“…Studies have been published on PET, single photon emission CT, and transthoracic Doppler flow assessment that showed impaired myocardial flow reserve in the chronic phase of Kawasaki disease with cardiac involvement [18,19].…”
Section: Kawasaki Diseasementioning
confidence: 99%