Transthoracic biopsy with core cutting needle (Trucut) for the diagnosis of mediastinal tumors

Zamboni, Mauro; Lannes, Deborah Cordeiro; Cordeiro, Paulo; Toscano, Edson; Torquato, Emanuel; Cordeiro, Samuel S. de Biasi; Cavalcanti, Aureliano

doi:10.1016/s2173-5115(09)70135-6

Cited by 3 publications

(2 citation statements)

References 13 publications

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“…Traditional methods for diagnosing mediastinal tumors include mediastinoscopy, thoracoscopy, and exploratory thoracotomy. These operations require general anesthesia and hospitalization [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

Incidental Diagnosis of Primary Pleural Liposarcoma in a COVID-19-Positive Patient

Harrasi¹,

Al-Kindi²,

Lawati³

et al. 2023

Cureus

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A few cases of primary liposarcoma of pleura have been reported worldwide. We report a young gentleman who was admitted with what was initially thought as coronavirus disease 2019 (COVID-19)-related pulmonary symptoms. His chest CT showed a large pleural effusion causing a mediastinal shift and compressing vital structures. He did not respond to conservative drainage intervention and subsequently underwent a left thoracotomy for his worsening clinical picture. He was found to have a large left pleural mass that was incompletely resected. Histopathology examination showed low-grade soft tissue sarcoma with lipogenic differentiation suggestive of myxoid liposarcoma. He was subsequently given adjuvant chemotherapy but succumbed and died because of the progression of the disease.

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Section: Discussionmentioning

confidence: 99%

Incidental Diagnosis of Primary Pleural Liposarcoma in a COVID-19-Positive Patient

Harrasi¹,

Al-Kindi²,

Lawati³

et al. 2023

Cureus

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“…Rita MONTEIRO et al, Massas mediastínicas , Acta Med Port. 2011; 24(6):899-904 O diagnóstico histológico é obtido por biópsia transtorácica, transbrônquica, mediastinoscopia, mediastinotomia anterior, vídeo-toracoscopia ou toracotomia 1,3,6,16 .…”

Section: Introductionunclassified

Massas mediastínicas: análise de uma casuística.

Monteiro

Alfaro²,

Correia³

et al. 2012

Acta Med Port

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Mediastinal masses are tumoral lesions arising from intra-thoracic organs. They are an infrequent diagnostic challenge, requiring a structured clinical and radiological approach.The study of the clinical, radiological and pathological characteristics, treatment and prognosis of patients, with mediastinal masses, admitted to an Internal Medicine ward in an University Hospital.A retrospective analysis of the medical records of patients with this diagnosis made between years 2000 and 2008.Twenty-eight patients were included (15F/13M), with a mean age of 55.5 years (17-88). Twenty-six patients presented with symptoms, most frequently, dyspnoea, fatigue, dry cough, chest pain and anorexia. At examination, six exhibited superior vena cava syndrome. Chest X-ray showed pathological changes in 26. Chest CT scan added relevant information in all cases whenever it was performed. Histology was most frequently obtained by mediastinoscopy, open surgical biopsy, percutaneous thoracic biopsy and at necropsy. Histological diagnosis was not possible in ten patients. Final diagnoses included: lymphoma in four patients; sarcoidosis, thymic hyperplasia and undifferentiated squamous carcinoma of unknown origin in two patients each; other diagnosis in single cases were: thyroid teratoma, thymoma, atrial myxoid malignant fibrous histiocytoma, ganglioneuroblastoma, neuroendocrine thymic carcinoma, squamous cell lung cancer and germinative cell tumour. Thirteen patients were submitted to surgery, chemo and/or radiotherapy. Fifteen patients died during admission or when in follow-up.At our center, mediastinal masses are frequently of a malignant origin, affecting relatively young people; a late diagnosis and an associated poor prognosis was the rule, prompting for early intervention to improve outcome.

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