“…Some authors defend the hypothesis that it represents the remnant of the ascending track followed by Rathke's pouch through the sphenoid bone from the nasopharynx up to the sella turcica 5,8,13,20,28 . This hypothesis is supported by histological studies that describe the presence of normal and tumoral pituitary tissue inside the channel 20 , by case reports of panhypopituitarism following adenoidectomy 8,13,28 , by Erdheim's theories and the case reports of infrasellar or nasopharyngeal craneopharyngiomas associated with this anomaly 3 , and by the presence of trans and intrasphenoidal encephaloceles 22,23,27 or by case reports of intrasphenoidal pituitary tissue in asymptomatic population 13,19 .…”