Transrectal biopsy of the prostate and bacteraemia

Thompson, Peter M.; Talbot, Richard; Packham, D. A.; Dulake, C.

doi:10.1002/bjs.1800670217

Cited by 61 publications

(26 citation statements)

References 14 publications

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“…Others demonstrated that approximately 70% of patients [4,8,9] experienced transitory bacteremia and between 21% and 53% [4,10] showed significant bacteriuria during or immediately after the procedure. These findings led several authors to investigate different preventive measures.…”

Section: Discussionmentioning

confidence: 99%

Transrectal ultrasound-guided prostate biopsy: is antibiotic prophylaxis necessary?

et al. 2006

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The aim of this study was to assess infectious complications in transrectal ultrasound-guided prostate biopsy (TRUSPB), comparing two groups of patients: one group with antibiotic prophylaxis and the other without prophylaxis. A total of 1,018 TRUSPBs were performed from April 1996 to July 2003. No antibiotic prophylaxis was given in the first 614; the remaining 404 procedures were performed under antibiotic prophylaxis. Biopsy complications were assessed at outpatient urologist visits after the procedure in the 212 first biopsies and by telephone interview in the remaining 806. A total of 78 infectious complications were found. Major infectious complications (n=41) were septic shock (n=3), sepsis (n=3), Fournier gangrene (n=1), urinary tract infection (n=2), and fever requiring hospital admission (n=32). Minor infectious complications were fever that did not require admission (n=29), prostatitis (n=6), and epididymitis (n=2). Infectious complications occurred in 63 of 614 (10.3%) procedures without antibiotic prophylaxis and in 15 of 404 (3.7%) of those with antibiotic prophylaxis (P=0.0001). Of the 41 major infectious complications, 31 (75.6%) occurred in procedures without antibiotic prophylaxis (n=583) versus ten (24.4%) in those with prophylaxis (n=394) (P=0.0410). In conclusion, transrectal ultrasound-guided biopsy of the prostate has a statistically significant higher risk of infectious complications when performed without antibiotic prophylaxis.

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Section: Discussionmentioning

confidence: 99%

Transrectal ultrasound-guided prostate biopsy: is antibiotic prophylaxis necessary?

et al. 2006

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“…2,6 Although many studies have reported the incidence of complications, they were not specifically designed to evaluate the true complication rate and its implications. [8][9][10][11][12] It is essential to have a clear understanding of the true morbidity of this procedure, and this would enable appropriate patient counseling.…”

Section: Introductionmentioning

confidence: 99%

Hemospermia following transrectal ultrasound-guided prostate biopsy: a prospective study

Manoharan

Ayyathurai

Nieder

et al. 2007

Prostate Cancer Prostatic Dis

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Hemospermia is known to be associated with transrectal ultrasound-guided prostate biopsy (TRUS-PB). The true incidence of hemospermia, its duration and implications are not well established. We performed a prospective observational study involving patients undergoing TRUS-PB for suspected prostate cancer at our institution. Sixty-three eligible men were included in the study. Most men (84%) undergoing TRUS-PB, who were able to ejaculate, experienced hemospermia, which was associated with some degree of anxiety. The mean duration of hemospermia was 3.5 (71.7) weeks. The number of ejaculations before the complete resolution of hemospermia was 8 (76.7). None of the clinical and pathological factors was a significant predictor of the duration of hemospermia. Patients should be adequately counseled before TRUS-PB to avoid undue anxiety and alterations in sexual activity.

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“…Thompson et al berichteten von signifikanten Bakteriämien nach transrektaler Prostatabiopsie in 73±100 % [19,20]. Die Häufigkeit entzündlicher Komplikationen kann durch eine prophylaktische Antibiotikagabe verringert werden [6,7,15].…”

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Komplikationen der TRUS-gesteuerten systematischen Sextantenbiopsie der Prostata

et al. 1999

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In einer prospektiven Untersuchung wurden die Komplikationen der transrektalen ultraschallgesteuerten (TRUS-gesteuerten) systematischen Sextantenbiopsie bei 1650 Patienten ausgewertet. Die Indikation zur Biopsie waren ein erhöhter PSA-Wert, suspekter Tastbefund und/oder suspekter Ultraschallbefund. Die Biopsien wurden ambulant unter antibiotischer Prophylaxe mit einem Gyrasehemmer durchgeführt. Schwere Komplikationen waren selten, eine kurzfristige Temperaturerhöhung über 38 C wurde von 2,1 % der Patienten gemessen. 12 Patienten (0,72 %) entwickelten nach der Sextantenbiopsie eine akute Prostatitis, die eine stationäre Aufnahme erforderlich machte. Geringe Blutbeimengungen zum Urin, Sperma oder Stuhl wurden von über 50 % der Patienten beobachtet, diese sistierten jedoch spontan bei allen Patienten. Eine therapiebedürftige Blutung wurde bei keinem Patienten beobachtet. Insgesamt stellt die transrektale ultraschallgesteuerte Prostatabiopsie unter Antibiotikaprophylaxe ein sicheres und komplikationsarmes Verfahren dar.

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Transrectal biopsy of the prostate and bacteraemia

Cited by 61 publications

References 14 publications

Transrectal ultrasound-guided prostate biopsy: is antibiotic prophylaxis necessary?

Transrectal ultrasound-guided prostate biopsy: is antibiotic prophylaxis necessary?

Hemospermia following transrectal ultrasound-guided prostate biopsy: a prospective study

Komplikationen der TRUS-gesteuerten systematischen Sextantenbiopsie der Prostata

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