Transpupillary Thermotherapy in the Treatment of Circumscribed Choroidal Hemangiomas

Vianna, Raul N. G.; Fernandes, Luiza Helena; Muralha, Acácio; Alves, Aderbal; Muralha, Lília; Muranaka, Eduardo

doi:10.1023/b:inte.0000031742.38421.d9

Cited by 7 publications

(2 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The use of PDT in the treatment of chronic CCSC has not been without complication, and RPE atrophy and juxtafoveal CNV have been reported after PDT 18,19. Trans-pupillary thermotherapy (TTT) has been advocated in the management of macular lesions, particularly in the treatment of CNV,20 choroidal melanoma,21,22 choroidal hemangioma,23 and CSC 24,25. The advantages of diode laser (810 nm) in the treatment of macular disease are related to low absorption by xanthophyll and poor absorption by hemoglobin (allowing treatment through preretinal and subretinal blood), with low energy delivery, thereby avoiding damaging photoreceptor cells.…”

Section: Introductionmentioning

confidence: 99%

Large-spot subthreshold transpupillary thermotherapy for chronic serous macular detachment

Giudice¹,

Belvis²,

Tavolato³

et al. 2011

OPTH

View full text Add to dashboard Cite

Purpose:To report the effect of subthreshold transpupillary thermotherapy (TTT) in treating serous detachment of the neurosensory retina secondary to chronic central serous chorioretinopathy (CCSC).Methods:Seven eyes from five patients with CCSC, persistent serous detachment of the neurosensory retina and a clinical course of between 12 and 60 months were treated. All eyes received large-spot TTT guided by indocyanine green angiography (ICGA). Subthreshold TTT was performed using an 810 nm diode laser with a spot size of 3.0 mm (power was set at 350 mW). Treatment was applied for 60 seconds to the areas of choroidal hyperfluorescence on ICGA.Results:The mean number of TTT sessions was 1.4 ± 0.5. All eyes were followed up for at least 6 months (mean 9.6 ± 3.2 standard deviation; range 6–12 months). The mean logarithm of the minimum angle of resolution best-corrected visual acuity was significantly better compared with baseline. All TTT-treated eyes had stable or improved vision (P < 0.001). Mean optical coherence tomography (OCT) central foveal thickness was significantly lower in all patients (P < 0.001) compared with pretreatment OCT, with a reduction in subretinal fluid and resolution of serous detachment associated with anatomical fovea restoration. No patient had any treatment-related side effects.Conclusion:Modified subthreshold TTT appears to have a beneficial effect in treating patients with CCSC and persistent neurosensory detachment. The encouraging results and lack of visually significant complications suggest that further investigation is warranted.

show abstract

Section: Introductionmentioning

confidence: 99%

Large-spot subthreshold transpupillary thermotherapy for chronic serous macular detachment

Giudice¹,

Belvis²,

Tavolato³

et al. 2011

OPTH

View full text Add to dashboard Cite

show abstract

“…A terapia térmica transpupilar (TTT) é uma modalidade de tratamento que utiliza a radiação infravermelha (comprimento de onda de 810 nm) para entregar calor de maneira lenta e uniforme no tumor (atingindo temperaturas entre 45 e 60 graus Célsius) promovendo desnaturação de proteína, danos na membrana celular, efeitos cromossomiais e alteração de vias bioquímicas que culminam com a necrose e redução da espessura tumoral. Casos de tratamentos efetivos com essa modalidade de LASER foram relatados (Othmane et al, 1999;Rapizzi;Grizzard;Capone, 1999;García-Arumí;Ramsay;Guraya, 2000;Fuchs et al, 2002;Vianna et al, 2004;Kivelä;Grange, 2011). A atrofia coroidal e as alterações pigmentares de EPR foram descritas após o tratamento, limitando o uso dessa modalidade em lesões subfoveais.…”

Section: Modalidades Terapêuticasunclassified

Avaliação in vivo da segurança de tartarato de metoprolol intravítreo em olhos com hemangioma circunscrito de coroide. Estudo fase I

Chaves

View full text Add to dashboard Cite

Agradeço às pessoas às quais dedico toda a minha vida, pois são a razão dela existir: meus pais, Ronaldo e Shirley. Muito obrigado pelo amor infinito, apoio e investimento constante nos meus estudos. Por terem me dado todas as ferramentas para que eu alcançasse meus sonhos, mesmo abdicando dos seus. Aos meus irmãosLuciano e Ângelo, à Danielle, ao Lucas e aos meus amigos próximos, pelo amor, companheirismo e apoio incondicional. Por estarem presentes e serem meu porto seguro. A todos os mestres e amigos da UFJF que me proporcionaram fundações sólidas. Em especial ao Prof. Dr. Leonardo Provetti Cunha, por despertar meu interesse pela Oftalmologia.

show abstract

Treatment of Serous Macular Detachment Associated With Circumscribed Choroidal Hemangioma

Kwon

Kim

Lee

et al. 2012

American Journal of Ophthalmology

View full text Add to dashboard Cite

Transpupillary Thermotherapy in the Treatment of Circumscribed Choroidal Hemangiomas

Abstract: TTT showed no deleterious side effects in treating serous macular detachment secondary to CCH, and must be regarded as a therapeutic alternative to manage selected cases.

Cited by 7 publications

References 14 publications

Large-spot subthreshold transpupillary thermotherapy for chronic serous macular detachment

Large-spot subthreshold transpupillary thermotherapy for chronic serous macular detachment

Avaliação in vivo da segurança de tartarato de metoprolol intravítreo em olhos com hemangioma circunscrito de coroide. Estudo fase I

Treatment of Serous Macular Detachment Associated With Circumscribed Choroidal Hemangioma

Contact Info

Product

Resources

About