Transporteurs d'iodures et fonction thyroïdienne

Massart, C.; Corbineau, E.

doi:10.1016/j.immbio.2006.04.003

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Sodium-iodide Symporter1

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“…SSF members actively transport anions into cells by using a Na + /K + electrochemical gradient that is generated by Na + /K + ATPase (Jung 2002). Following uptake into thyroid cells, iodide is then transported to the follicular lumen and oxidised by the thyroid peroxidase in a reaction that promotes the iodination of tyrosyl residues of the thyroid hormones tri-and tetra-iodothyronine (T3 and T4) (Massart and Corbineau 2006). 9.1).…”

Section: Sodium-iodide Symportermentioning

confidence: 99%