Background and Objectives
The 30āmin rule has been used to maintain a core temperature (CT) of redābloodācell (RBC) units below 10Ā°C during transportation. We evaluated the utility of temperatureāsensitive indicators (TIs) to monitor the surface temperature (ST) of RBC units and to explore whether TIs can help with compliance with the 30āmin rule by extrapolating or correlating temperature change with time.
Materials and Methods
Two US FDAāapproved TIs, SafeāTāVue 10 (STV10; Temptime Corporation, Morris Plains, NJ, USA) and Timestrip Blood Temp 10 (BT10; Timestrip UK Ltd, Cambridge, UK), were attached to 50 RBC units. After issue, their colour change indicating 10Ā°C was monitored, and temperature excursions were measured by standard reading. In additional 18 RBC units, both ST and CT were monitored simultaneously.
Results
In 50 RBC units, 94% of STV10 and 100% of BT10 showed colour change indicating 10Ā°C within 30Ā min; 4% of STV10 and 18% of BT10 showed it during transportation. The time for colour change indicating 10Ā°C differed significantly between STV10 and BT10 (19Ā·0 vs. 5Ā·6Ā min, PĀ <Ā 0Ā·001). In additional 18 RBC units, 83Ā·3% of STV10, 100% of BT10 and 88Ā·9% of CT reached 10Ā°C within 30Ā min, and the time for colour change indicating 10Ā°C was 24Ā·4Ā min in STV10, 14Ā·6Ā min in BT 10 and 24Ā·2Ā min in CT (PĀ <Ā 0Ā·001).
Conclusion
In two TIs, the time for colour change indicating 10Ā°C varied considerably. To enhance the utility of TIs, further improvement and standardization would be needed.