Transport of three veterinary antimicrobials from feedlot pens via simulated rainfall runoff

Sura, Srinivas; Degenhardt, Dani; Cessna, Allan J.; Larney, Francis J.; Olson, A. R.; McAllister, Tim A.

doi:10.1016/j.scitotenv.2015.03.080

Cited by 27 publications

(36 citation statements)

References 48 publications

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“…Consequently, application of raw or processed (composted or stockpiled) manure to fertilize agricultural land is a major route by which antimicrobials enter the broader environment. Subsequent transport of antimicrobials in snowmelt or rainfall runoff from manure‐amended crop (Amarakoon et al., ; Dolliver & Gupta, ; Hoese et al., ; Kuchta et al., ) or grass land (Burkhardt, Stamm, Waul, Singer, & Müller, ; Kuchta & Cessna, ; Stoob, Singer, Mueller, Schwarzenbach, & Stamm, ), and from feedlots (Sura et al., ) and manure composting and stockpiling facilities (Dolliver & Gupta, ; Sura et al., ) can lead to their presence in surface receiving waters.…”

Section: Introductionmentioning

confidence: 99%

Persistence of the antimicrobials lincomycin, chlortetracycline, and sulfamethazine in prairie wetlands

et al. 2020

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Antimicrobials used in livestock production can be present in manure via excretion in the feces and/or urine. Application of raw or processed (composted or stockpiled) manure to crop and pasture land as a plant nutrient source can result in antimicrobial transport to surface waters via rainfall or snowmelt runoff. Little is known regarding antimicrobial persistence in aquatic ecosystems. Consequently, dissipation of environmentally relevant concentrations of three veterinary antimicrobials (lincomycin, chlortetracycline, and sulfamethazine) was studied in three wetlands on the Canadian Prairies. Study wetlands were fortified in the fall to simulate antimicrobial transport via rainfall runoff from fall manure applications to the wetland catchments. After fortification, water column concentrations of all three antimicrobials decreased through September and October. Plotting natural logarithm values of antimicrobial concentration against time resulted in linear relationships for all three antimicrobials, indicating that the summation of all dissipation processes for each antimicrobial could be described by first‐order kinetics. The slopes of the three plots were significantly different, indicating that the order of dissipation was lincomycin < sulfamethazine < chlortetracycline. Consequently, the dissipation DT50 (time required for 50% antimicrobial dissipation) values for lincomycin (14.0 d), sulfamethazine (7.0 d), and chlortetracycline (3.3 d) were significantly different. The longer DT50 values of lincomycin and sulfamethazine suggest that environmentally relevant concentrations of these antimicrobials may affect bacterial production in prairie wetlands.

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Section: Introductionmentioning

confidence: 99%

Persistence of the antimicrobials lincomycin, chlortetracycline, and sulfamethazine in prairie wetlands

et al. 2020

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“…In 2011, 135,000 metric tons of antibiotics were purchased in the United States for livestock use, which represents 70% of total national consumption (FDA, 2012). A growing body of research has established that agricultural soils treated with animal manures and adjacent waters tend to have elevated levels of various antibiotic‐resistant bacteria (ARBs) and antibiotic resistance genes (ARGs; Heuer et al, 2011; Marti et al, 2013; Cook et al, 2014; Sura et al, 2015; Liu et al, 2016; Yang et al, 2016). Use of antibiotics in dairy cattle is of particular interest because, although antibiotics use during milking periods is banned in the United States and much of the world, they are still used frequently to treat and prevent problematic infections, such as mastitis and metritis (Sura et al, 2015).…”

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confidence: 99%

Fate of Pirlimycin and Antibiotic‐Resistant Fecal Coliforms in Field Plots Amended with Dairy Manure or Compost during Vegetable Cultivation

et al. 2018

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Identification of agricultural practices that mitigate the environmental dissemination of antibiotics is a key need in reducing the prevalence of antibiotic-resistant bacteria of human health concern. Here, we aimed to compare the effects of crop (lettuce [ L.] or radish [ L.]), soil amendment type (inorganic fertilizer, raw dairy manure, composted dairy manure, or no amendment), and prior antibiotic use history (no antibiotics during previous lactation cycles vs. manure mixed from cows administered pirlimycin or cephapirin) of manure-derived amendments on the incidence of culturable antibiotic-resistant fecal coliforms in agricultural soils through a controlled field-plot experiment. Antibiotic-resistant culturable fecal coliforms were recoverable from soils across all treatments immediately after application, although persistence throughout the experiment varied by antibiotic class and time. The magnitude of observed coliform counts differed by soil amendment type. Compost-amended soils had the highest levels of cephalosporin-resistant fecal coliforms, regardless of whether the cows from which the manure was derived were administered antibiotics. Samples from control plots or those treated with inorganic fertilizer trended toward lower counts of resistant coliforms, although these differences were not statistically significant. No statistical differences were observed between soils that grew leafy (lettuce) versus rooted (radish) crops. Only pirlimycin was detectable past amendment application in raw manure-amended soils, dissipating 12 to 25% by Day 28. Consequently, no quantifiable correlations between coliform count and antibiotic magnitude could be identified. This study demonstrates that antibiotic-resistant fecal coliforms can become elevated in soils receiving manure-derived amendments, but that a variety of factors likely contribute to their long-term persistence under typical field conditions.

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“…This magnitude of loss may represent the maximum loss (worst-case scenario for loss) of runoff after rainfall on windrows of composting manure. In contrast, surface runoff from feedlot pens after simulated rainfall onto manure (0.48 kg kg −1 water content) on the floor of feedlot pens was only 19% (Sura et al, 2015).…”

Section: Runoff From Windrowsmentioning

confidence: 89%

“…A pressurized liquid extraction (PLE) method, described in Sura et al (2015), was used to extract antimicrobials from the freeze-dried manure. In brief, ground freeze-dried manure (1 g) mixed with Ottawa sand was placed in a 33-mL stainless steel extraction cell and extracted (ASE 200, Dionex) with 0.2 mol L −1 citric acid buffer (pH 5.0) at 75°C and 105.5 kg cm −2 pressure in two steps.…”

Section: Composting Manure Samplesmentioning

confidence: 99%

Transport of Three Antimicrobials in Runoff from Windrows of Composting Beef Cattle Manure

et al. 2016

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Rain runoff from windrowed or stockpiled manure may contain antimicrobials with the potential to contaminate surface and ground water. To quantify the concentration of antimicrobials transported in runoff from windrowed manure, antimicrobials were administered continuously in feed to beef cattle () as follows: 44 mg of chlortetracycline kg feed (dry weight), a 1:1 mixture of 44 mg of chlortetracycline and 44 mg sulfamethazine kg feed, and 11 mg of tylosin kg feed. Cattle in a fourth treatment group received no antimicrobials (control). Manure from the cattle was used to construct two windrows per treatment. On Days 2 and 21 of composting, a portable Guelph Rainfall Simulator II was used to apply deionized water at an intensity of 127 mm h to each windrow, and the runoff was collected. Manure samples were collected before rain simulations on Days 2 and 21 of composting for antimicrobial analysis. On Day 2, average concentrations of chlortetracycline, sulfamethazine, and tylosin in manure were 2580, 450, and 120 μg kg, respectively, with maximum concentrations in runoff of 2740, 3600, and 4930 μg L, respectively. Concentrations of all three antimicrobials in runoff were higher ( < 0.05) on Day 2 than on Day 21, reflecting the higher concentrations in manure on Day 2. Maximum estimated masses of chlortetracycline, sulfamethazine, and tylosin that could be transported in runoff from a windrow (3 m long, 2.5 m wide, 1.5 m high) were approximately 0.87 to 0.94, 1.57, and 1.23 g, respectively. This study demonstrates the importance of windrow composting in reducing antimicrobial concentrations in manure. The runoff from windrows can be a source of antimicrobials and demonstrates the need for containment of runoff from composting facilities to mitigate antimicrobial contamination of surface and groundwater resources.

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Transport of three veterinary antimicrobials from feedlot pens via simulated rainfall runoff

Cited by 27 publications

References 48 publications

Persistence of the antimicrobials lincomycin, chlortetracycline, and sulfamethazine in prairie wetlands

Persistence of the antimicrobials lincomycin, chlortetracycline, and sulfamethazine in prairie wetlands

Fate of Pirlimycin and Antibiotic‐Resistant Fecal Coliforms in Field Plots Amended with Dairy Manure or Compost during Vegetable Cultivation

Transport of Three Antimicrobials in Runoff from Windrows of Composting Beef Cattle Manure

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