Abstract:Interaction between low concentrations of cortisol-4-C14 or progesterone-4-C14 and serum proteins was investigated by paper-electrophoretic methods in human serum albumin solution as well as in human and rat serum. Between 2 and 10% of cortisol and between 70 and 90% of progesterone were found to be bound and thus transported by human albumin. Similar transport values were observed in paper-chromatographic studies in which the steroids migrated in aqueous solution, in the presence and absence of serum proteins… Show more
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