Transplantation oj the Kidney, Spring

Goodwin, Willard E.; Martin, D. C.

doi:10.1097/00007890-196401000-00065

Cited by 8 publications

(9 citation statements)

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“…The results presented by these acknowledged experts were extremely discouraging. Less than 10% of their several hundred allograft recipients had survived as long as 3 months (Goodwin and Martin 1963). Of patients treated with total body irradiation, only six had approached or achieved 1 year survival (Starzl 2000).…”

Section: National Research Council Conferencementioning

confidence: 99%

Historical Overview of Transplantation

Barker

Markmann

2013

Cold Spring Harbor Perspectives in Medicine

165

114

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Except for legends and claims of miracles, most histories of transplantation cover only the last 60 years because there were no earlier successes. However, the story of even this era has been documented in such rich detail that a full account would fill several volumes. Thus, this brief summary must be limited to highly selected "landmarks." Some landmarks had an immediate impact, but the importance of others went unrecognized for decades. Some findings that deserved landmark status were overlooked or forgotten, whereas others of no biological significance had major impact. Placing these events in perspective is challenging. Several of transplantation's pioneers are still alive, and most of the others are within living memory. Virtually all of them have produced their own accounts. For the most part, they agree on what the "landmarks" are, but their differences in emphasis and perspective make an interesting story.

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Section: National Research Council Conferencementioning

confidence: 99%

Historical Overview of Transplantation

Barker

Markmann

2013

Cold Spring Harbor Perspectives in Medicine

165

114

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“…During the 1960s, the work of Roy Calne and others indicated that immunosuppression could be achieved chemically using compounds like 6-mercaptopurine Open Journal of Organ Transplant Surgery and azathioprine [3]. Despite these advances, patient survival was quite low with most patients living only 3 -6 months after transplantation [4]. However, in 1963, Tom Starzl showed that, by using a combination of azathioprine and prednisone, 1-year patient survival rates could exceed 70% [5].…”

Section: Introductionmentioning

confidence: 99%

New Frontiers in Transplantation and Stem Cell Technology: A Brief Synopsis

Javadi¹,

Brooks²,

Obi-Umahi³

et al. 2018

OJOTS

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Since the first kidney transplant was performed in 1954 immense progress has been made in the world of transplantation. Modern immunosuppressive regimens have led to increasing graft and patient survival after solid organ transplantation. Furthermore, these advances have opened the door to new fields of transplantation such as composite tissue allotransplantation. These developments have made possible numerous types of transplantation including, but not limited to face, penile, and uterine transplantation. Moreover, innovations in genetic engineering and stem cell technology have contributed to rapid developments in the fields of xenotransplantation and the engineering of functional organs from induced pluripotent stem cells. As the prevalence of chronic diseases rises, so too will the necessity for organ transplantation. Thus, the transplant innovations of the modern era need to be expanded upon so as to continue to discover new ways to address organ shortages and the complications of transplantation.

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“…Martin 13 and more recently by Groth. 14 By 1951, Küss et al 22 and other members of the French school of surgery 11,40 had virtually standardized the procedure of kidney transplantation to the iliac fossa, anastomosing the renal to the pelvic vessels of the recipient in much the same way as is practiced today.…”

mentioning

confidence: 97%

Personal Reflections in Transplantation

Starzl¹

1978

Surgical Clinics of North America

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Transplantation oj the Kidney, Spring

Cited by 8 publications

References 0 publications

Historical Overview of Transplantation

Historical Overview of Transplantation

New Frontiers in Transplantation and Stem Cell Technology: A Brief Synopsis

Personal Reflections in Transplantation

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