Transplantation of the heart after circulatory death of the donor: time for a change in law?

Tibballs, James; Bhatia, Neera

doi:10.5694/mja15.00295

Cited by 11 publications

(11 citation statements)

References 9 publications

(6 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Implementation of such programs in other countries, including Canada, has been hindered by practical considerations and ethical debates within the medical community both for and against DCDD heart programs. [11][12][13][14] We conducted a national survey to determine the attitudes and opinions of Canadian healthcare providers towards cardiac DCDD and perceived barriers to its implementation.…”

Section: Résumémentioning

confidence: 99%

Attitudes of healthcare providers towards cardiac donation after circulatory determination of death: a Canadian nation-wide survey

Honarmand

Leigh

Basmaji

et al. 2020

Can J Anesth/J Can Anesth

View full text Add to dashboard Cite

The number of patients on cardiac transplant waitlists exceeds the number of available donor organs. Cardiac donation is currently limited to those declared dead by neurologic criteria in all but three countries. Cardiac donation after circulatory determination of death (cardiac DCDD) can be conducted using direct procurement and perfusion (DPP) or normothermic regional perfusion (NRP). Implementation of cardiac DCDD in many countries has been slowed by ethical debates within the donation and transplantation community. We conducted a national survey to determine the perceptions of healthcare providers regarding cardiac DCDD. Methods We conducted an electronic survey of 398 healthcare providers who are involved in the management of heart donors and/or heart transplant recipients in Canada (226 nurses, 82 critical care physicians, 31 donation specialists, and 59 transplant specialists). Our primary outcomes were their attitudes towards and concerns regarding cardiac DCDD protocols This article is accompanied by an editorial. Please see Can J Anesth 2020; 67: this issue.

show abstract

Section: Résumémentioning

confidence: 99%

Attitudes of healthcare providers towards cardiac donation after circulatory determination of death: a Canadian nation-wide survey

Honarmand

Leigh

Basmaji

et al. 2020

Can J Anesth/J Can Anesth

View full text Add to dashboard Cite

show abstract

“…It has been argued that if the diagnosis of death by circulatory criteria necessitates the irreversible cessation of cardiac activity, its restoration violates the dead donor rule, which states that organ recovery can only occur after death. [9][10][11] NRP is possibly more controversial than DPP because it involves restoration of circulation within the donor's body after surgically interrupting the cerebral vasculature to ensure that circulatory flow to the brain is not restored. In some jurisdictions, such as Australia, where the definition of death is based on permanent cessation of systemic circulation, its restoration within the donor body would violate such a definition.…”

Section: Cardiac Dcdd Protocolsmentioning

confidence: 99%

Cardiac donation after circulatory determination of death: protocol for a mixed-methods study of healthcare provider and public perceptions in Canada

et al. 2020

View full text Add to dashboard Cite

IntroductionCardiac transplantation remains the best treatment for patients with end-stage heart disease that is refractory to medical or device therapies, however, a major challenge for heart transplantation is the persistent discrepancy between the number of patients on waiting lists and the number of available hearts. While other countries (eg, UK, Australia and Belgium) have explored and implemented alternative models of transplantation, such as cardiac donation after circulatory determination of death (DCDD) to alleviate transplantation wait times, ethical concerns have hindered implementation in some countries. This study aims to explore the attitudes and opinions of healthcare providers and the public about cardiac DCDD in order to identify and describe opportunities and challenges in ensuring that proposed cardiac DCDD procedures in Canada are consistent with Canadian values and ethical norms.Methods and analysisThis study will include two parts that will be conducted concurrently. Part 1 is a qualitative study consisting of semi-structured interviews with Canadian healthcare providers who routinely care for organ donors and/or transplant recipients to describe their perceptions about cardiac DCDD. Part 2 is a convergent parallel mixed-methods design consisting of a series of focus groups and follow-up surveys with members of the Canadian general public to describe their perceptions about cardiac DCDD.Ethics and disseminationThis study has been approved by the Research Ethics Board at Western University. The findings will be presented at regional and national conferences and reported in peer-reviewed publications.

show abstract

“…Some have argued that the determination of death by circulatory criteria requires that the cessation of cardiac function is permanent, and thus the mere possibility of restoring cardiac function would imply that death never occurred, and the ''Dead Donor Rule'' would be violated by retrieving the heart for donation. 3,7,8 Indeed, the Dead Donor Rule stipulates that an organ donor's cause of death cannot be organ donation itself. Others have suggested that determination of death by circulatory criteria only requires cessation of circulation, where there is no intent to resuscitate the presumptive donor.…”

Section: Concerns Regarding Cardiac Dcddmentioning

confidence: 99%

Heart recovery after circulatory determination of death: time for public engagement

Ball

Honarmand

Leigh

et al. 2019

Can J Anesth/J Can Anesth

View full text Add to dashboard Cite

Transplantation of the heart after circulatory death of the donor: time for a change in law?

Cited by 11 publications

References 9 publications

Attitudes of healthcare providers towards cardiac donation after circulatory determination of death: a Canadian nation-wide survey

Attitudes of healthcare providers towards cardiac donation after circulatory determination of death: a Canadian nation-wide survey

Cardiac donation after circulatory determination of death: protocol for a mixed-methods study of healthcare provider and public perceptions in Canada

Heart recovery after circulatory determination of death: time for public engagement

Contact Info

Product

Resources

About