Transplantation of the adult kidney into the very small child: Long-term outcome

Miller, Laurie C.; Bock, Glenn H.; Lum, Caliann T.; Najarían, John S.; Mauer, S. Michael

doi:10.1016/s0022-3476(82)80563-5

Cited by 50 publications

(19 citation statements)

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“…Miller, Bock, Lum, Najarian, and Mauer (1982) followed 12 children who received transplants of adult kidneys at ages 11 months to 45 months. They reported that at the time of transplant all patients displayed delayed development assessed by the Denver Developmental Screening Test (DDST), with motor skills being most severely affected.…”

Section: Renal Transplantationmentioning

confidence: 99%

“…In a given study, the timing of posttransplant assessment can vary considerably, from several months to years. In one study (Miller et al, 1982), the length of follow-up assessment varied by as much as 7% years. In general, when follow-up assessments are conducted at somewhat systematic intervals (e.g., Fennell et al, 1984), the duration of follow-up has been limited to a period of no longer than 1 year.…”

Section: Follow-up Assessmentsmentioning

confidence: 99%

“…Especially in infant assessment, instruments that were developed by the investigators (e.g., Warady et al, 1988) without adequate psychometric investigations are often employed. Similarly, instruments having inadequate psychometric properties or that were designed solely for screening purposes (e.g., the Denver Developmental Screening Test) have been employed in some studies (e.g., Miller et al, 1982). In addition, assessments usually have been conducted by an author who was fully aware of the subject's clinical status (i.e., pre-versus posttransplant).…”

Section: Dependent Measuresmentioning

confidence: 99%

See 2 more Smart Citations

Cognitive Development and Learning in the Pediatric Organ Transplant Recipient

Hobbs¹,

Sexson

1993

J Learn Disabil

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Although organ transplantation is considered a viable treatment approach for end-stage organ disease, few empirical investigations have assessed the effects of transplantation on the cognitive development and learning of pediatric organ transplant recipients. This article reviews studies evaluating neurocognitive changes following organ transplantation in pediatric end-stage renal and liver disease. Despite numerous methodological problems inherent in the investigations examined, the findings of some studies are suggestive of potential neurocognitive benefits associated with organ transplantation. Recommendations are made regarding methodological improvements for future investigations assessing neurocognitive outcomes of organ transplantation.

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Section: Renal Transplantationmentioning

confidence: 99%

Section: Follow-up Assessmentsmentioning

confidence: 99%

Section: Dependent Measuresmentioning

confidence: 99%

See 1 more Smart Citation

Cognitive Development and Learning in the Pediatric Organ Transplant Recipient

Hobbs¹,

Sexson

1993

J Learn Disabil

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show abstract

“…Causes are multifactorial: toxic effects of uremia, malnutrition and frequent hospitalization 8,9 . Gross motor function is severely affected by muscle weakness due to malnutrition 10 . HC is normal at birth in these patients 8,11 .…”

Section: Discussionmentioning

confidence: 99%

“…Complications in the central nervous system are frequent and usually severe in infants. Developmental delay occurs in 60–80% of patients younger than 1 year of age and in approximately 50% of patients aged 2–3 years, and occurs more frequently in patients with severe growth retardation 8–13 …”

Section: Discussionmentioning

confidence: 99%