Transplantation of a Cadaveric Liver Allograft With Right Lobe Cavernous Hemangioma, Without Back-Table Resection: A Case Report

Nikeghbalian, S; Kazemi, Kourosh; Salahi, Heshmatollah; Bahador, Ali; Davari, Hamid Reza; Jalaeian, Hamed; Rasekhi, Alireza; Nejatollahi, Seyed Mohammad Reza; Gholami, Somayeh; Malekhosseini, Seyed Ali

doi:10.1016/j.transproceed.2006.12.040

Cited by 4 publications

(4 citation statements)

References 9 publications

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“…As shown in Table 1 , seven cases of donor livers with hemangiomas have been reported previously [10] , [11] , [12] , [13] , [14] , [15] , [16] . There are only two reports of left lateral segment from a living donor containing hemangioma transplanted to pediatric patients but not to adult patients [12] , [15] .…”

Section: Discussionmentioning

confidence: 99%

“…The hemangioma usually remains asymptomatic [3] and has a benign course [4] , [5] , [6] , although symptomatic hemangiomas may rarely require either interventional or surgical treatment [7] , [8] , [9] . There are few published reports regarding liver transplantation using liver allografts with hemangiomas [10] , [11] , [12] , [13] , [14] , [15] , [16] . In not only deceased donor liver transplantation but also living donor liver transplantation (LDLT), liver allografts with hemangiomas have been utilized for transplantation.…”

Section: Introductionmentioning

confidence: 99%

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Successful adult-to-adult living donor liver transplantation using liver allograft after the resection of hemangioma: A suggestive case for a further expansion of living donor pool

Onishi

Kamei

Imai

et al. 2015

International Journal of Surgery Case Reports

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HighlightsDonor organ scarcity is the major problem in the field of liver transplantation.Extended criteria donor for living donor liver transplantation (LDLT) is crucial.This is the first adult-to-adult LDLT using liver allograft with benign hemangioma.Liver allograft with hemangioma is a remarkable strategy to resolve organ shortage.This case is so suggestive for a safe expansion of living donor pool in LDLT.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Successful adult-to-adult living donor liver transplantation using liver allograft after the resection of hemangioma: A suggestive case for a further expansion of living donor pool

Onishi

Kamei

Imai

et al. 2015

International Journal of Surgery Case Reports

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“…There are several case reports of successful transplantation of livers with giant hemangiomas, with or without resection in individual cases. [63][64][65][66][67] In contrast, the use of donor hearts containing benign atrial myxomas is questioned by some authors, [68][69][70] and indeed, primary benign tumors themselves may provide a reason for heart transplantation. 71,72 Other benign tumors have the potential to undergo malignant transformation, and this should be kept in mind when such tumors are encountered.…”

Section: Special Considerations For Donors With Benign Tumorsmentioning

confidence: 99%

“…OPTN/UNOS data on past history of cancer in potential organ donors in the US were first summarized and later updated by Kauffman et al 49,74,75 Overall, a total of 1069 donors provided 2508 organs. Of those tumors that were specified, the ten resulting in the most frequent organ allografts (number of transplants in parentheses) included nonmelanoma skin cancer (776), uterine cervical cancer (336), glioblastoma multiforme (175), astrocytoma (152), melanoma (140), breast cancer (126), meningioma (80), ovarian carcinoma (75), prostate carcinoma (66), and endometrial carcinoma (65). 74 The only reported tumor transmission involved a donor with a history of melanoma 32 years prior, with transmission in one of six organ recipients.…”

Section: Potential Donors With a History Of Cancermentioning

confidence: 99%

Organ transplantation from deceased donors with cancer: is it safe?

Nalesnik¹,

Ison²

2011

OAS

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The availability of donor organs continues to be insufficient to meet the needs of patients actively waiting for transplant. Consequently, there is continuing pressure to increase the donor organ pool while simultaneously assuring safety for the recipient population. The complication of donor malignancy transmission has been documented almost from the beginning of transplantation, and continues to be a concern today. The anecdotal nature of case reports and compiled series ensures that clinical decisions related to organ use from donors with malignancy will of necessity continue to be made on the basis of low-level evidence. Despite this limitation, the literature indicates that not all donor neoplasms have the same risk for transmission to the recipient, and it is necessary to consider the specific malignancy affecting the donor, as well as the condition of the recipient, before a decision is made to transplant or discard a given organ. Published cases suggest that certain forms of neoplasia, such as melanoma, choriocarcinoma, sarcoma, small cell carcinoma, or metastatic carcinomas serve as strong contraindications to organ donation. In contrast, considerable experience exists to suggest that certain tumors of the central nervous system, small subclinical prostate carcinomas, or small renal cell carcinomas resected prior to transplant, among other tumors, should not in themselves disqualify an individual from donating organs in the appropriate circumstance. This review presents the case for considering organ transplantation in the setting of certain donor malignancies and discusses factors to be weighed in such decisions. Additionally, donors with a history of cancer are considered, and features that may aid in reaching a conclusion for or against transplantation of organs from these patients are presented.

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Transplantation of a 2-year-old deceased-donor liver to a 61-year-old male recipient

Dai

Sharr

Chok

et al. 2015

Asian Journal of Surgery

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The suitable size of a graft is a key element in the success of liver transplantation. A small-for-size liver graft is very likely to sustain a significant degree of injury as a result of ischemia, preservation, reperfusion, and rejection. Usually, small-for-size grafts are a concern in living-donor liver transplantation rather than in deceased-donor liver transplantation. Here, we describe the successful transplantation of a liver from a 2-year-old deceased donor to a 61-year-old male recipient who suffered from liver failure related to hepatitis B. No report of successful deceased-donor liver transplantation with discrepancies between donor and recipient age and size to such an extent has been found in the literature. Despite unusually large discrepancies, with effort in minimizing the ischemic time, revised surgical techniques, and strong regenerative power of the "young" graft, the old patient's liver function gradually returned to normal. This again proves that the definition of a "suitable graft" evolves with time and experience.

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Transplantation of a Cadaveric Liver Allograft With Right Lobe Cavernous Hemangioma, Without Back-Table Resection: A Case Report

Cited by 4 publications

References 9 publications

Successful adult-to-adult living donor liver transplantation using liver allograft after the resection of hemangioma: A suggestive case for a further expansion of living donor pool

Successful adult-to-adult living donor liver transplantation using liver allograft after the resection of hemangioma: A suggestive case for a further expansion of living donor pool

Organ transplantation from deceased donors with cancer: is it safe?

Transplantation of a 2-year-old deceased-donor liver to a 61-year-old male recipient

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