Transplant Patient With Skin Nodules

A rare case of cutaneous acanthamoebiasis in a renal transplant patient

“…Diagnosis can be made by culture using a nonnutrient agar on a plate containing Escherichia coli [8]. A polymerase chain reaction (PCR) has also been developed which detects a highly conserved, yet specific sequence, to the Acanthamoeba genus [2].…”

Answer to May 2019 Photo Quiz

“…Disseminated infections usually occur in solid organ transplant recipients, AIDS patients, or patients with hematological malignancies (4). Acanthamoeba infections have rarely been reported to occur in lung transplant recipients, and to our knowledge, only nine other cases have been reported in this setting (5,6). This infection is rare because it occurs in the context of both immunodeficiency and, probably, a particular epidemiology (e.g., frequent contact with water).…”

Morphological Description of the Early Events during the Invasion of Acanthamoeba castellanii Trophozoites in a Murine Model of Skin Irradiated under UV-B Light

“…The GAE is a subacute or chronic infection causing necrosis and inflammatory lesions, whose entry route can be hematogenous or through the respiratory tract, affecting mainly immunocompromised people [ 5 ], with multiple sclerosis or diabetes [ 2 , 6 , 7 ]. Nevertheless, clinical GAE cases have occurred in immunocompetent people and patients with organ transplants [ 8 , 9 , 10 , 11 ]. No less important is the AK—a painful corneal infection with a chronic course that usually occurs in contact lens wearers, characterized by, progressive corneal epithelium necrosis and stromal lamella destruction, which can cause a decrease in visual acuity, the loss of vision or eyeball [ 12 , 13 ].…”