Transplacental bluetongue infection in cattle

Clercq, Kris De; Vandenbussche, F.; Vandemeulebroucke, E.; Vanbinst, T.; Leeuw, Ilse De; Verheyden, Bart; Goris, Nesya; Mintiens, Koen; Meroc, Estelle; Herr, Cécile; Hooybergs, J; Houdart, P.; Sustronck, Bart; Deken, R. De; Maquet, G.; Bughin, J.; Saulmont, Marc; Lebrun, Marielle; Bertels, G.; Miry, C

doi:10.1136/vr.162.17.564

Cited by 39 publications

(18 citation statements)

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“…The BTV-8 strain also demonstrated the ability to cross the ruminant placenta a (Backx et al, 2009;Darpel et al, 2009;De Clerq et al, 2008;Desmecht et al, 2008;Menzies et al, 2008;Saegerman et al, 2010;van der Sluijs et al, 2011;Vercauteren et al, 2008), a property that had previously only generally been associated with the vaccination of pregnant animals with MLV strains (Flanagan and Johnson, 1995;Parsonson et al, 1987;Schultz and Delay, 1955).. The BTV-8 strain also appears to have had an increased tendency to be secreted in the semen of infected rams and bulls.…”

Section: Why Is It Important To Identify the Molecular Determinants Tmentioning

confidence: 95%

Bluetongue virus genetic and phenotypic diversity: Towards identifying the molecular determinants that influence virulence and transmission potential

Coetzee

Vuuren

Stokstad

et al. 2012

Veterinary Microbiology

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Section: Why Is It Important To Identify the Molecular Determinants Tmentioning

confidence: 95%

Bluetongue virus genetic and phenotypic diversity: Towards identifying the molecular determinants that influence virulence and transmission potential

Coetzee

Vuuren

Stokstad

et al. 2012

Veterinary Microbiology

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“…Furthermore, laboratory experiments suggest that BTV may be capable of persistently infecting T cells in sheep, reappearing in the skin over a month after the viraemic period has ended (Takamatsu et al 2003), although other researchers have failed to duplicate this result , suggesting that it may be dependent on factors such as breed of sheep and virus strain. Transplacental infection may also occur De Clerq et al 2008). Meanwhile, adult Culicoides mortality is greatly reduced at cool temperatures, with individuals of some temperate vector species capable of surviving for three months or more at 10°C (Lysyk and Danyk 2007), while at such temperatures, virus replication may effectively cease (Mullens et al 1995).…”

Section: Bluetongue Epidemiologymentioning

confidence: 97%

Bluetongue in Europe: vectors, epidemiology and climate change

2008

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Bluetongue (BT) is an economically important disease of ruminants resulting from infection with bluetongue virus (BTV). Historically, BT outbreaks in Europe were rare and short-lived. However, during the last 10 years, BTV has become firmly established in southern Europe and, since 2006, has begun to occur in northern Europe. There is a substantial body of evidence linking this emergence to climate change. In this paper, we summarise the recent emergence of BTV in Europe, review the known links between climate and BTV transmission, and discuss gaps in our knowledge of the epidemiology of BT and how they might be filled by current and future research.

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“…In cattle and goats, BTV infections are usually subclinical, whereas natural infection of BTV-8 [6,7,16,25] and experimental infection with some BTV strains [26] of pregnant cows during early gestation may result in congenital brain defects, in particular hydranencephaly of the foetuses or calves [27]. Infection with BT in pregnant animals, causes abortions, giving birth to stillborn offsprings or malformated calves and lambs depending on the stage gravidity [2,5,27,28].…”

Section: Discussionmentioning

confidence: 99%

“…The expansion of BTV in Europe has forced a reevaluation of the importance of Palaearctic Culicoides species *Address correspondence to this author at the Komenskeho 73, Clinic of Ruminants, University of Veterinery Medicine amd Pharmacy in Kosice, 041 81 Kosice, Slovak Republic; Tel: 0421948500956; Fax: 0421556711674; E-mails: lackova_z@azet.sk, dudro@mail.t-com.sk in transmission [2][3][4], as well as the importance of secondary transmission routes [1], such as transplacental transmission [1,[5][6][7], in facilitating the persistence of the virus.…”

Section: Introductionmentioning

confidence: 99%

Clinical and Laboratory Picture in Calves in Rearing with Incidence Bluetongue

Lacková¹,

Bíreš²,

Smaržík³

et al. 2012

TOASJ

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Abstract:The aim of the study was to analyze clinical and laboratory findings in calves after birth and on the fifth day of age in the farm with the occurrence of bluetongue disease. Presence of a disease has been confirmed in heifers that were imported to Slovakia from France. In August 2008 a total of 132 heifers were imported to Slovakia. Based on serological examinations, presence of antibodies reactive to the virus was proved. In 5 heifers without the presence of virus reactive antibodies, virus was diagnosed. Of 120 calves born, 13 were virologically positive. 10 calves born in the farm were included in the survey. 2 of them were virologically positive, born to serologically negative dams. In 8 control calves born in the same time no antibodies were detected after birth. During clinical examination no clinical signs typical for bluetongue disease were observed. Laboratory examination in the monitoring period showed increase in hepatic profile parameters in virologically positive calves. In virologically negative calves we have detected increased hepatic profile parameters on the 1st day of life. On the 5th day in this group some of the parameters decreased to the physiological levels. Alterations in the selected biochemical parameters that we have detected in virologically positive and negative animals were likely not influenced by infection with bluetongue.

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Transplacental bluetongue infection in cattle

Cited by 39 publications

References 0 publications

Bluetongue virus genetic and phenotypic diversity: Towards identifying the molecular determinants that influence virulence and transmission potential

Bluetongue virus genetic and phenotypic diversity: Towards identifying the molecular determinants that influence virulence and transmission potential

Bluetongue in Europe: vectors, epidemiology and climate change

Clinical and Laboratory Picture in Calves in Rearing with Incidence Bluetongue

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