Transpiration‐Inspired Fabric Dressing for Acceleration Healing of Wound Infected with Biofilm

Abstract

In chronic wound management, efficacious handling of exudate and bacterial infections stands as a paramount challenge. Here we introduced a novel biomimetic fabric, inspired by the natural transpiration mechanisms in plants. Uniquely, the fabric combines a commercial polyethylene terephthalate (PET) fabric with asymmetrically grown 1D rutile titanium dioxide (TiO2) micro/nanostructures, emulating critical plant features: hierarchically porous networks and hydrophilic water conduction channels. This structure endows the fabric with exceptional antigravity wicking‐evaporation performance, evidenced by a 780% one‐way transport capability and a 0.75 g h−1 water evaporation rate, which significantly surpasses that of conventional moisture‐wicking textiles. Moreover, the incorporated 1D rutile TiO2 micro/nano‐structures presented solar‐light induced antibacterial activity, crucial for disrupting and eradicating wound biofilms. The biomimetic transpiration fabric has been employed to drain exudate and eradicate biofilms in Staphylococcus aureus (S. aureus)‐infected wounds, demonstrating a much faster infection eradication capability compared to clinically common ciprofloxacin irrigation. These findings illuminate the path for developing high‐performance, textile‐based wound dressings, offering efficient clinical platforms to combat biofilms associated with chronic wounds.This article is protected by copyright. All rights reserved

Innovative approaches in skin therapy: bionanocomposites for skin tissue repair and regeneration

“…The use of BNCs with antimicrobial properties can significantly reduce the risk of infection and improve patient outcomes. 9,10…”

“…In one study, a novel biomimetic fabric, drawing inspiration from natural transpiration mechanisms in plants, was unveiled. 13 This fabric ingeniously merged a commercial polyethylene terephthalate fabric with asymmetrical growth of one-dimensional rutile titanium dioxide (TiO 2 ) micro/nanostructures. It exhibited essential plant characteristics, such as hierarchically porous networks and hydrophilic water conduction channels.…”

“…It demonstrated a substantially faster infection eradication potential in comparison to the commonly used ciprofloxacin irrigation method. 13 These significant findings paved the way for the development of high-performance textile-based wound dressings. These dressings offered efficient clinical solutions to combat biofilms associated with chronic wounds, marking a notable advancement in wound care technology.…”