Transperineal template-guided biopsy for diagnosis of prostate cancer in patients with at least two prior negative biopsies

Klatte, Tobias; Swietek, Natalia; Schatzl, Georg; Waldert, Matthias

doi:10.1007/s00508-013-0421-4

Cited by 13 publications

(5 citation statements)

References 17 publications

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“…We found 39 retrospective studies, 46 prospective studies, and 13 RCTs where periprocedural antibiotics were administered [12] , [13] , [14] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [35] , [36] , [37] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [47] , [48] , [49] , [50] , [51] , [52] , [53] , [54] , [55] , [56] , [57] , [58] , [59] , [60] , [61] , [62] , [63] , [64] , [65] , [67] , [68] , [70] , [71] , [72] , [73] , [74] , [75] , [76] , [77] , [78] , [79] , [80] , [81] , [82] , [83] , [84] , [85] , …”

Section: Evidence Synthesisunclassified

Role of Prophylactic Antibiotics in Transperineal Prostate Biopsy: A Systematic Review and Meta-analysis

Basourakos

Alshak

Lewicki

et al. 2022

European Urology Open Science

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Section: Evidence Synthesisunclassified

Role of Prophylactic Antibiotics in Transperineal Prostate Biopsy: A Systematic Review and Meta-analysis

Basourakos

Alshak

Lewicki

et al. 2022

European Urology Open Science

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“…However, this approach is still offered in only a small percentage of patients, in particular in conjunction with pre-biopsy MRI, as shown by an audit carried out on behalf of Urological Society of Australia and New Zealand [ 6 , 7 ]. Despite this, several previous studies have confirmed its usefulness in men with previous negative biopsies [ 4 ].…”

Section: Introductionmentioning

confidence: 98%

“…Transperineal route of needle biopsies under guidance of a TRUS probe is emerging as a second line investigation in the diagnostic care pathway, particularly in men with previous negative biopsies and rising PSA [ 3 ]. The burgeoning interest in this approach is due to improved sampling of anterolateral part of the gland, better information on grade and volume of cancer and perhaps a reduced risk of infection compared to transrectal route [ 4 , 5 ]. However, this approach is still offered in only a small percentage of patients, in particular in conjunction with pre-biopsy MRI, as shown by an audit carried out on behalf of Urological Society of Australia and New Zealand [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Combined T2 and diffusion-weighted MR imaging with template prostate biopsies in men suspected with prostate cancer but negative transrectal ultrasound-guided biopsies

et al. 2016

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PurposeTransperineal template prostate (TPB) biopsy has been shown to improve prostate cancer detection in men with rising PSA and previous negative TRUS biopsies. Diagnostic performance of this approach especially MR imaging and using reliable reference standard remains scantly reported.Materials and methodsA total of 200 patients, who were previously TRUS biopsy negative, were recruited in this study. All the participants had at least 28-core TPB under general anesthetic within 8 weeks of previous negative TRUS biopsies. In 15 men undergoing laparoscopic radical prostatectomy, prostate specimens were sectioned using custom-made molds and analyzed by experienced pathologist as a feasibility study.ResultsIn total, 120 of 200 patients (60 %) had positive TPB biopsy results. All of these men had at least one negative biopsy from transrectal route. T2 diffusion-weighted MR imaging showed no lesion in almost one-third of these men (61/200; 30.5 %). Out of these, 33 (33/61; 54 %) showed malignancy on TPB including high-grade tumors (>Gleason 7). Out of 15 patients underwent surgery with a total of 52 lesions (mean 3.5) on radical prostatectomy histology analyses, TPB detected 36 (70 %) lesions only. Some of these lesions were Gleason 7 and more mostly located in the posterior basal area of prostate.ConclusionsTransperineal template biopsy technique is associated with significantly high prostate cancer detection rate in men with previous negative TRUS biopsies, however compared to radical prostatectomy histology map, a significant number of lesions can still be missed in the posterior and basal area of prostate.

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“…Сатурационная промежностная биопсия, по мнению многих авторов, обладает преимуществом при повторном исследовании, частота обнаружения РПЖ ва-рьирует от 22,7 до 58% [21][22][23].…”

Section: Discussionunclassified

Procedure for transperineal mapping biopsy in the diagnosis of prostate cancer

Stepanov¹,

Alekseev²,

Каприн³

et al. 2016

Onkol. Z. im. P.A. Gercena

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Ключевые слова: рак предстательной железы, биопсия предстательной железы, сатурационная биопсия, трансперинеаль-ная биопсия.Objective: to study the capabilities of transperineal mapping biopsy (TpMB) to diagnose localized prostate cancer (pC). Subjects and methods. Twenty patients with suspected pC who had undergone TpMB of the prostate under transrectal ultrasound guidance were examined. Results. pC was diagnosed in 10 (50%) patients. Further comparison of the results of planned morphological examination with the data of TpMB showed no significant differences in the detection of pathological foci and in gleason scores. Conclusion. TpMB is an effective technique to verify pC. The results of this biopsy may be used for the planning of its treatment using focal therapy options.

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Transperineal template-guided biopsy for diagnosis of prostate cancer in patients with at least two prior negative biopsies

Abstract: A 24-core TPB is a safe procedure with a high PCa detection rate. Few of the detected PCa are clinically insignificant. Men with at least two negative transrectal biopsies may be counseled to undergo TPB.

Cited by 13 publications

References 17 publications

Role of Prophylactic Antibiotics in Transperineal Prostate Biopsy: A Systematic Review and Meta-analysis

Role of Prophylactic Antibiotics in Transperineal Prostate Biopsy: A Systematic Review and Meta-analysis

Combined T2 and diffusion-weighted MR imaging with template prostate biopsies in men suspected with prostate cancer but negative transrectal ultrasound-guided biopsies

Procedure for transperineal mapping biopsy in the diagnosis of prostate cancer

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