Transoral Robotic Surgery Alone for Oropharyngeal Cancer

Choby, Garret; Kim, Jeehong; Ling, Diane C.; Abberbock, Shira; Mandal, Rajarsi; Kim, Seungwon; Ferris, Robert L.; Duvvuri, Umamaheswar

doi:10.1001/jamaoto.2015.0347

Cited by 71 publications

(81 citation statements)

References 19 publications

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“…While most patients in this series had a temporary feeding tube, few had prolonged dependence, generally less than 2-3 weeks. These data compares well with a recent report, as well as other data, documenting functional outcomes following TORS, with a similar number of patients requiring prolonged enteral access and most reporting a favorable MDADI score [26,[43][44][45]. Additionally, the need for a tracheostomy was limited, and all patients who underwent tracheostomy at the time of initial resection were decannulated within 1 month of surgery.…”

Section: Discussionsupporting

confidence: 85%

Transoral endoscopic head and neck surgery (eHNS) for minor salivary gland tumors of the oropharynx

et al. 2017

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Background: Transoral endoscopic head and neck surgery (eHNS), including transoral laser microsurgery (TLM) and transoral robotic surgery (TORS), provides access to subsites in the head and neck that have traditionally been difficult to approach. Minor salivary gland tumors, while relatively uncommon, are frequently malignant and can occur at sites in the oropharynx accessible by transoral eHNS. Presented here is the largest review to date of patients with minor salivary gland tumors of the oropharynx managed with transoral eHNS as primary or salvage therapy. Methods: A retrospective chart review was performed, including data from 20 patients with minor salivary gland tumors of the oropharynx managed with transoral eHNS at 2 tertiary, academic medical centers. Details of tumor pathology, margin analysis, adjuvant therapy, and an assessment of oncologic outcome were included. Results: The base of tongue was the most common tumor site (75%). Adenoid cystic carcinoma (ACC) accounted for most cases (35%), and negative margins were obtained in most (95%) through an endoscopic-only approach. Overall, 50% of patients received post-operative radiation therapy. Postoperative complications were limited, with one patient (5%) returning to the OR for control of post-operative oropharyngeal bleeding. On average follow-up of 36 months, 90% of patients were alive with no evidence of recurrence.

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Section: Discussionsupporting

confidence: 85%

Transoral endoscopic head and neck surgery (eHNS) for minor salivary gland tumors of the oropharynx

et al. 2017

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“…Only 1.0% of TORS patients compared to 5.1% of open surgery patients had fistula formation [3]. These are in line with other non-comparative studies which reported that TORS shortens the time to resumption of ambulation and speech functions and are related to lower rates of postoperative complications such as infections and fistula formation [6], [7], [8], [9]. Despite these known advantages, we report a case here to illustrate the possibility of invasive candidiasis in a patient who has undergone TORS.…”

Section: Introductionsupporting

confidence: 84%

A case report of invasive candidiasis and fungal osteomyelitis mimicking oropharyngeal carcinoma recurrence in an immunocompetent patient following transoral robotic surgery

Tan

Low

Roche³

et al. 2017

International Journal of Surgery Case Reports

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“…Reports of swallowing function (< 2 years) after transoral laser surgery and robotic surgery are not well studied; however, several studies report low rates of dysphagia and gastrostomy dependence (0% to 7%) beyond the first year postsurgery. 29,34,50 …”

Section: Discussionmentioning

confidence: 99%

Current Role of Surgery in the Management of Oropharyngeal Cancer

Turner

Byrd

Ferris

2016

JOP

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The 1990s saw an increased use of chemoradiotherapy protocols, commonly referred to as organ-sparing therapy, for the treatment of oropharyngeal cancer after the Groupe d’Oncologie Radiothérapie Tête Cou trial. Since that time, human papillomavirus–associated oropharyngeal squamous cell carcinoma has been identified as a unique disease, with improved survival regardless of treatment modality. The improved outcomes of this population has led to re-evaluation of treatment paradigms in the past decade, with a desire to spare young, human papillomavirus–positive patients the treatment-related toxicities of chemoradiotherapy and to use new minimally invasive surgical techniques to improve outcomes. Numerous retrospective and prospective studies have investigated the role of surgery in treatment of oropharyngeal carcinoma and have demonstrated equivalent oncologic outcomes and improved functional outcomes compared with chemoradiotherapy protocols. Ongoing and future clinical trials may help delineate the role of surgery in the future.

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Transoral Robotic Surgery Alone for Oropharyngeal Cancer

Abstract: Appropriately selected patients who undergo TORS alone for oropharyngeal squamous cell carcinoma experience acceptable short- and long-term QOL outcomes.

Cited by 71 publications

References 19 publications

Transoral endoscopic head and neck surgery (eHNS) for minor salivary gland tumors of the oropharynx

Transoral endoscopic head and neck surgery (eHNS) for minor salivary gland tumors of the oropharynx

A case report of invasive candidiasis and fungal osteomyelitis mimicking oropharyngeal carcinoma recurrence in an immunocompetent patient following transoral robotic surgery

Current Role of Surgery in the Management of Oropharyngeal Cancer

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