Transoral Incisionless Fundoplication 2.0 Procedure Using EsophyX™ for Gastroesophageal Reflux Disease

Abstract

At short-term follow-up, the TIF procedure is associated with an excessive early symptomatic failure rate, and a high surgical re-intervention rate. This procedure should not be performed outside of a clinical trial.

Comprehensive evaluation of endoscopic fundoplication using the EsophyXTM device

“…We did not experience any gastric or esophageal perforations or bleeding as previously reported in prior studies where the rates of significant bleeding requiring transfusion or gastroesophageal perforations have ranged from 0 to 8% and from 0 to 5%, respectively [5,7,8,10,11,20,21]. One patient did have a minor proximal mucosal tear, from device insertion, which required no additional therapy.…”

Transoral incisionless fundoplication (TIF 2.0) with EsophyX for gastroesophageal reflux disease: long-term results and findings affecting outcome

“…Only one, fairly recent study concluded that, at short-term follow-up, the TIF procedure was associated with an excessive early symptomatic failure rate and a high surgical re-intervention rate [32]. The present study assessed the results of the TIF 2.0 procedure at 6 months, 1 and 2 years in a series of patients with documented GERD; it also attempted to identify anatomical, functional, and procedure-related factors influencing successful outcome.…”

Effectiveness of a transluminal endoscopic fundoplication for the treatment of pediatric gastroesophageal reflux disease

“…One center reported disappointing results with complications including an esophageal perforation, hemorrhage requiring transfusion, and permanent tongue numbness. Device failure using TIF 2.0 occurred in 3/19 cases (15.8%) with 10/19 patients converted to laparoscopic fundoplication [14]. The efficacy of the procedure could possibly correlate with the experience of the surgeon, but this stresses the potential complications of the TIF procedure.…”