“…Three days later, the patient underwent percutaneous PFO closure with the Amplatzer septal occluder (AGA Medical, Golden Valley, Minnesota). Prompted by previous reports, [7][8][9][10][11] we decided to perform the procedure under guidance of TEENW, with the purpose to avoid either two vascular accesses or endotracheal intubation with further general anesthesia. [12][13][14][15] With the patient in supine position, a miniaturized, 10 Fr, multifrequency (5.5-10 MHz), monoplane probe developed for intracardiac echocardiography (ICE) (AcuNav, Acuson/ Siemens, Mountain View, CA), was inserted into the esophagus, only with a lubricant jelly, through a nostril (Fig.…”