Transmission optical coherence tomography based measurement of optical material properties

Trull, Anna K.; Horst, Jelle van der; Bijster, J. G.; Kalkman, Jeroen

doi:10.1364/oe.23.033550

Cited by 9 publications

(7 citation statements)

References 24 publications

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“…The solution of this framework in the sense of the simulation of detectable scattered intensity is not restricted to a dimension or a direction. Transmission optical coherence tomography based measurements of optical material properties is one experimental platform for our methodology [115][116][117]. Here we present results for the temporal evolution of the transmission cross section σ, and the mean square width σ 2 respectively, Fig.…”

Section: Temporal Evolution Of the Transmission Cross Section And Thementioning

confidence: 96%

Self-consistent quantum field theory for the characterization of complex random media by short laser pulses

Lubatsch

Frank

2020

Phys. Rev. Research

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We present a quantum field theoretical method for the characterization of disordered complex media with short laser pulses in an optical coherence tomography setup (OCT). We solve this scheme of coherent transport in space and time with weighted essentially non-oscillatory methods (WENO). WENO is preferentially used for the determination of highly non-linear and discontinuous processes including interference effects and phase transitions like Anderson localization of light. The theory determines spatio-temporal characteristics of the scattering mean free path and the transmission cross section that are directly measurable in time-of-flight (ToF) and pump-probe experiments. The results are a measure of the coherence of multiple scattering photons in passive as well as in optically soft random media. Our theoretical results of ToF are instructive in spectral regions where material characteristics such as the scattering mean free path and the diffusion coefficient are methodologically almost insensitive to gain or absorption and to higher-order nonlinear effects. Our method is applicable to OCT and other advanced spectroscopy setups including samples of strongly scattering mono-and polydisperse complex nano-and microresonators.

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Section: Temporal Evolution Of the Transmission Cross Section And Thementioning

confidence: 96%

Self-consistent quantum field theory for the characterization of complex random media by short laser pulses

Lubatsch

Frank

2020

Phys. Rev. Research

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“…The filter operation in (15) and (16) in the -domain is represented by a multiplication of the OCT signal in thedomain by the functions…”

Section: Oct Spectral Sampling and Detectionmentioning

confidence: 99%

“…For mathematical clarity it is assumed that the refractive index is spatially invariant and completely described by the polynomial expansion of (22). Performing a Taylor expansion of the phase = ( )2 [16] (see Appendix A), the interference spectrum is…”

Section: Oct Signal In a Dispersive Mediummentioning

confidence: 99%

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Fourier-Domain Optical Coherence Tomography Signal Analysis and Numerical Modeling

Kalkman

2017

International Journal of Optics

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In this work the theory of the optical coherence tomography (OCT) signal after sampling, in dispersive media, with noise, and for a turbid medium is presented. The analytical theory is demonstrated with a one-dimensional numerical OCT model for (single) reflectors, dispersive media, and turbid media. For dispersive media the deterioration of the OCT axial resolution is quantified analytically and numerically. The OCT signal to noise ratio (SNR) is analyzed in the Fourier-domain and simulated with the numerical model. For an SNR based on the OCT intensity the conventional shot noise limited SNR is derived whereas for an SNR based on the OCT amplitude a 6.7 dB higher SNR is demonstrated. The OCT phase stability is derived in the Fourier-domain as 2SNR−1 and is validated using the numerical OCT model. The OCT single scattering model is simulated with the one-dimensional numerical model and applied to the simulation of an OCT image of a two-layered sample.

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“…As the bones are highly scattering media, the authors decided to use the optical coherence tomography (OCT, pioneered by David Huang, James G. Fujimoto, and co-workers in 1991 [ 18 ]). In addition to OCT, other measurement techniques for highly scattering media investigation, such as methods using integration spheres [ 19 , 20 ], time-of-flight spectroscopy [ 21 , 22 ], photoacoustic microscopy and spectroscopy [ 23 , 24 ], optical diffuse tomography [ 25 , 26 ], optical diffraction tomography [ 27 , 28 ], optical projection tomography (or optical transmission tomography) [ 29 , 30 ], and transmission optical coherence tomography [ 31 , 32 ], are known. However, these methods either may only be performed in vitro (which is a major limitation if future clinical applications are considered) or cannot provide additional information on bone properties (such as birefringence) with high spatial resolution, unlike polarization-sensitive OCT (PS-OCT).…”

Section: Introductionmentioning

confidence: 99%

The Optical Coherence Tomography and Raman Spectroscopy for Sensing of the Bone Demineralization Process

Głowacki

Kamińska

Gnyba

et al. 2021

Sensors

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The presented research was intended to seek new optical methods to investigate the demineralization process of bones. Optical examination of the bone condition could facilitate clinical trials and improve the safety of patients. The authors used a set of complementary methods: polarization-sensitive optical coherence tomography (PS-OCT) and Raman spectroscopy. Chicken bone samples were used in this research. To stimulate in laboratory conditions the process of demineralization and gradual removal of the hydroxyapatite, the test samples of bones were placed into 10% acetic acid. Measurements were carried out in two series. The first one took two weeks with data acquired every day. In the second series, the measurements were made during one day at an hourly interval (after 1, 2, 3, 5, 7, 10, and 24 h). The relation between the content of hydroxyapatite and images recorded using OCT was analyzed and discussed. Moreover, the polarization properties of the bones, including retardation angles of the bones, were evaluated. Raman measurement confirmed the disappearance of the hydroxyapatite and the speed of this process. This work presents the results of the preliminary study on the possibility of measuring changes in bone mineralization by means of the proposed methods and confirms their potential for practical use in the future.

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Transmission optical coherence tomography based measurement of optical material properties

Cited by 9 publications

References 24 publications

Self-consistent quantum field theory for the characterization of complex random media by short laser pulses

Self-consistent quantum field theory for the characterization of complex random media by short laser pulses

Fourier-Domain Optical Coherence Tomography Signal Analysis and Numerical Modeling

The Optical Coherence Tomography and Raman Spectroscopy for Sensing of the Bone Demineralization Process

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