transmission of the Ambystoma tigrinum virus to alternative hosts

Jancovich, James K.; Davidson, Elizabeth W.; Seiler, April; Jacobs, Bertram L.; Collins, James P.

doi:10.3354/dao046159

Cited by 67 publications

(62 citation statements)

References 17 publications

(22 reference statements)

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“…There are several ways that chelonians and amphibians might be exposed to the same virus. Previous studies in salamanders have shown that transmission can occur through cannibalism of infected individuals (Jancovich et al, 2001;Pearman et al, 2004). Box turtles are omnivorous, and tortoises, although normally herbivorous, may opportunistically feed on carrion.…”

Section: Discussionmentioning

confidence: 99%

Ranavirus Infection of Free-Ranging and Captive Box Turtles and Tortoises in the United States

Johnson¹,

Pessier²,

Wellehan³

et al. 2008

Journal of Wildlife Diseases

143

102

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ABSTRACT:Iridoviruses of the genus Ranavirus are well known for causing mass mortality events of fish and amphibians with sporadic reports of infection in reptiles. This article describes five instances of Ranavirus infection in chelonians between 2003 and 2005 in Georgia, Florida, New York, and Pennsylvania, USA. Affected species included captive Burmese star tortoises (Geochelone platynota), a free-ranging gopher tortoise (Gopherus polyphemus), free-ranging eastern box turtles (Terrapene carolina carolina), and a Florida box turtle (Terrepene carolina bauri). Evidence for Ranavirus infection was also found in archived material from previously unexplained mass mortality events of eastern box turtles from Georgia in 1991 and from Texas in 1998. Consistent lesions in affected animals included necrotizing stomatitis and/or esophagitis, fibrinous and necrotizing splenitis, and multicentric fibrinoid vasculitis. Intracytoplasmic inclusion bodies were rarely observed in affected tissues. A portion of the major capsid protein (MCP) gene was sequenced from each case in 2003-2005 and found to be identical to each other and to Frog virus 3 (FV3) across 420 base pairs. Ranavirus infections were also documented in sympatric species of amphibians at two locations with infected chelonians. The fragment profiles of HindIIIdigested whole genomic DNA of Ranavirus, isolated from a dead Burmese star tortoise and a southern leopard frog (Rana utricularia) found nearby, were similar. The box turtle isolate had a low molecular weight fragment that was not seen in the digestion profiles for the other isolates. These results suggest that certain amphibians and chelonians are infected with a similar virus and that different viruses exist among different chelonians. Amphibians may serve as a reservoir host for susceptible chelonians. This report also demonstrated that significant disease associated with Ranavirus infections are likely more widespread in chelonians than previously suspected.

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Section: Discussionmentioning

confidence: 99%

Ranavirus Infection of Free-Ranging and Captive Box Turtles and Tortoises in the United States

Johnson¹,

Pessier²,

Wellehan³

et al. 2008

Journal of Wildlife Diseases

143

102

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show abstract

“…In particular, it appears that fi sh and at least some reptiles are less susceptible to ATV and FV3-like ranaviruses than amphibians (Jancovich et al 2001 ;Picco et al 2010 ;Allender et al 2013b ;Brenes et al 2014a ). Several studies have demonstrated little or no transmission of ATV (Jancovich et al 2001 ;Picco et al 2010 ) and FV3 to fi sh (Ariel et al 2010 ;Gobbo et al 2010 ;Bang Jensen et al 2011a ;but see Bang Jensen et al 2011b ). Similarly, amphibians may be less susceptible to fi sh ranaviruses.…”

Section: Susceptibility To Ranaviruses Among Speciesmentioning

confidence: 99%

Ranavirus Ecology and Evolution: From Epidemiology to Extinction

et al. 2015

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“…Although originally thought to be restricted to urodeles (Jancovich et al 2001 ), ATV was later shown to be pathogenic to anurans (Schock et al 2008 ). Experimental infection of largemouth bass was successful, but inoculated animals experienced no mortality or disease (Picco et al 2010 ).…”

Section: Interclass Transmission Of Ranavirusesmentioning

confidence: 99%