Transmission of different variants of PCV2 and viral dynamics in a research facility with pigs mingled from PMWS-affected herds and non-affected herds

Abstract

Transmission of different variants of PCV2 and viral dynamics in a research facility with pigs mingled from PMWS-affected herds and non-affected herds, Veterinary Microbiology (2008Microbiology ( ), doi:10.1016Microbiology ( /j.vetmic.2009 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

Swine influenza virus infection dynamics in two pig farms; results of a longitudinal assessment

“…Closed separations between pens which do not allow direct physical contact between pigs from different pens are often considered as a preventive measure against dissemination of airborne pathogens, including SIV [10,30]. In our study, the lack of transmission among pigs housed in different pens with closed separations indicates that it would be advisable to design farm facilities with closed partitions between pens in order to minimize spread of SIV infection.…”

Association of concurrent porcine circovirus (PCV) 2a and 2b infection with PCV associated disease in vaccinated pigs

“…Although the recent genetic shift from PCV2a to PCV2b genotype occurred almost simultaneously with the onset of severe PCVAD outbreaks in the late 2005 in North America (Patterson and Opriessnig, 2010), neither genotype was found to be directly correlated with more severe disease under controlled experimental conditions Opriessnig et al, 2008;Dupont et al, 2009). More recently, there is evidence pointing towards a possible interaction between PCV2a and PCV2b allowing improved replication efficiency of the viruses in vitro and in vivo (Khaiseb et al, 2011;Guo et al, 2011) and increasing the virulence of PCVAD in the gnotobiotic pig model (Harding et al, 2010).…”

Experimental Airborne Transmission of Porcine Postweaning Multisystemic Wasting Syndrome

“…Real-time PCR was performed as previously described [25]. The PCV2 genome of selected samples was PCR amplified in three overlapping reactions and sequenced as previously described [15, 26]. …”

“…The high prevalence of PCV2 in almost all herds of all pig-producing countries indicates that the transmission of PCV2 is very effective [12–15]. In contrast, only a few studies have been performed on the “transmission” of the PCV2-associated disease complexes (PCVDs), that is, whether PMWS can be “transmitted” from PMWS-affected to PMWS-free pigs.…”