“…Out of her 119 publications before 1978, she published some 20 articles on chromosome 21, wrote some 15 reviews and books on DS, and made 14 more DS surveys. These papers covered the area of etiology, genetic counseling, prenatal diagnosis, and its cost benefit analysis, mortality, cause of death and life‐tables, cytogenetical and genealogical study, incidence study and cytogenetical epidemiology, the effect of parent's age, and the origin of the extra chromosome 21 [Mikkelsen, 1966a,b, 1967a,b, 1969, 1970, 1971a,b; Mikkelsen and Stene, 1970, 1972; Mikkelsen et al, 1976a,b, 1990; Øster et al, 1975].…”