Transmission Electron Microscopy Observations of Micelle Structure in a Vinyl Acetate-based Microemulsion

Del-Real, Alicia; Garcóa-Garduño, Margarita V.; Castaño, V. M.

doi:10.1080/00914039808033879

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Size Shape and Polydispersity Index (Pdi) Determination1

Microemulsions In a New Vision For An Optimized Acne Ther1

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Cited by 2 publications

(2 citation statements)

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“…Other methods that are also frequently employed for determination of micellar size and shape include scanning electron microscopy (SEM) [190], transmission electron microscopy (TEM) [191,192], and atomic force microscopy (AFM) [193]. Although SEM enjoys high resolution, its use is hindered by the fact that the sample should be able to withstand high vacuum and be conductive (which is done by coating gold on their surface).…”

Section: Size Shape and Polydispersity Index (Pdi) Determinationmentioning

confidence: 99%

Polymeric micelles: authoritative aspects for drug delivery

Kulthe

Choudhari

Inamdar

et al. 2012

Designed Monomers and Polymers

187

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Section: Size Shape and Polydispersity Index (Pdi) Determinationmentioning

confidence: 99%

Polymeric micelles: authoritative aspects for drug delivery

Kulthe

Choudhari

Inamdar

et al. 2012

Designed Monomers and Polymers

187

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“…The cosurfactant will be concentrated at the interface, among surfactant particles [ 186 , 187 ]. The system will be characterized by a free energy that will assure the microemulsifying process of droplets with a size of 1–100 nm which cannot be observed at a macroscale level, but only using fine experimental techniques like transmission electron microscopy (TEM) [ 185 , 188 ]. In this way, will be discovered particles with a specific assembly.…”

Section: Microemulsions In a New Vision For An Optimized Acne Thermentioning

confidence: 99%

Foray into Concepts of Design and Evaluation of Microemulsions as a Modern Approach for Topical Applications in Acne Pathology

et al. 2020

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With a fascinating complexity, governed by multiple physiological processes, the skin is considered a mantle with protective functions which during lifetime are frequently impaired, triggering dermatologic disorders. As one of the most prevalent dermatologic conditions worldwide, characterized by a complex pathogenesis and a high recurrence, acne can affect the patient’s quality of life. Smart topical vehicles represent a good option in the treatment of a versatile skin condition. By surpassing the stratum corneum known for diffusional resistance, a superior topical bioavailability can be obtained at the affected place. In this direction, the literature study presents microemulsions as a part of a condensed group of modern formulations. Microemulsions are appreciated for their superior profile in matters of drug delivery, especially for challenging substances with hydrophilic or lipophilic structures. Formulated as transparent and thermodynamically stable systems, using simplified methods of preparation, microemulsions have a simple and clear appearance. Their unique structures can be explained as a function of the formulation parameters which were found to be the mainstay of a targeted therapy.

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Transmission Electron Microscopy Observations of Micelle Structure in a Vinyl Acetate-based Microemulsion

Cited by 2 publications

References 20 publications

Polymeric micelles: authoritative aspects for drug delivery

Polymeric micelles: authoritative aspects for drug delivery

Foray into Concepts of Design and Evaluation of Microemulsions as a Modern Approach for Topical Applications in Acne Pathology

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