Transmembrane serine protease 2, a SARS-CoV-2 internalization protease, correlates with clinical outcome, molecular features, and immunotherapy response in colorectal cancer
Chenjing Zhu,
Jianfeng Wu,
Vishal G. Shelat
et al.
Abstract:Background
Transmembrane serine protease 2 (TMPRSS2) mediates the entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into host cells. The relevant research indicates the intestine to be a target of SARS-CoV-2 infection, and thus we aimed to investigate the correlation between
TMPRSS2
expression and the prognosis, molecular features, and immunotherapy response in patients with colorectal cancer (CRC).
Methods
The Cancer Genom… Show more
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