Translesional pressure and flow velocity after thrombolysis: Assessment of suboptimal angioplasty for serial lesions

Abstract

Translesional pressure and flow velocity observations in the right coronary artery remain among the most difficult data to interpret because of variation in the location and relative size of branches, and unsuspected diffuse disease. Use of distal hyperemic response and translesional pressure gradients provides the most accurate assessment of serial lesions in such patients. In addition, the use of intracoronary thrombolysis can improve the angiographic appearance of lesions and facilitate later successful interventions. The post-infarction distal microvascular responsiveness may be impaired and, thus, abnormal coronary reserve values in this particular setting should be considered with lesion specific indicators of successful recanalization.