Translational Research in Audiology: Presence in the Literature

Abstract

Translational research is a process that focuses on advancing basic research-based clinical solutions and is characterized by a structured process accelerating the implementation of scientific discoveries in healthcare. Translational research originated in oncology but has spread to other disciplines in recent decades. A translational project may refer to pharmacological research, the development of non-pharmacological therapies, or to disease monitoring processes. Its stages are divided into basic research focused on the clinical problem (T0), testing the developed means in humans (T1), conducting trials with patients (T2), implementation and dissemination of successful approaches (T3), and improving community health (T4). Many audiological studies are translational in nature. Accordingly, this scoping review aimed to evaluate the use of the terms “translational audiology” and “translational research in audiology” in the literature and examine the goals of the identified studies. PubMed and Web of Science search identified only two publications meeting the search criteria. We conclude that identifying translational audiological studies in the literature may be hampered by the lack of use of the terms “translational audiology” or “translational research”. We suggest using these terms when describing translational work in audiology, with a view to facilitating the identification of this type of research and credit it appropriately.

Universal Recommendations on Planning and Performing the Auditory Brainstem Responses (ABR) with a Focus on Mice and Rats

“…Translational research aims to apply basic research findings to clinical practice. A translational project in audiology may involve pharmacological research, the development of non-pharmacological therapies, or disease monitoring [ 1 ]. The auditory brainstem response (ABR), also known as brainstem auditory evoked potentials (BAEPs) and short-latency auditory evoked potentials (SLAEPs), is a sensitive tool for determining the therapeutic potential of hearing loss therapies [ 2 , 3 , 4 , 5 ] and for diagnosing auditory nerve and brainstem dysfunction.…”

Translational Research in Audiology

“…Among the many benefits associated with using the term "translational audiology" is identifying this type of research as a distinct stream in the science of audiology and emphasizing its practical application in clinical work. How often the term "translational audiology" is used in the literature, what articles have been published using the term, and the rationale and implications of such publications can be found in the review "Translational Research in Audiology: Presence in the Literature" [1].…”