Translational public health care perspective: Intravitreal treatment of neovascular age‐related macular degeneration has revolutionized clinical ophthalmology

Bloch, Sune Land; Larsen, Michael

doi:10.1111/aos.12680

Cited by 6 publications

(4 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The use of intravitreal anti-VEGF injections is increasing globally, and in the United States, their annual number has surpassed that of cataract surgeries (Williams 2014;Lee et al 2016). Intravitreal injections with anti-VEGF or corticosteroids have drastically improved visual outcomes in patients with various exudative retinal diseases (Bloch & Larsen 2015). Mean age of patients receiving intravitreal injections is reported to be at approximately 70 years in many developed countries (Schmidt-Erfurth et al 2014;Xu & Tan 2017;Ziemssen et al 2017).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Previous intravitreal injection as a risk factor of posterior capsule rupture in cataract surgery: a systematic review and meta‐analysis

Bjerager

Dijk

Holm

et al. 2022

Acta Ophthalmologica

View full text Add to dashboard Cite

Purpose Intravitreal injections and cataract surgery are two common procedures in the elderly. Posterior capsular rupture (PCR) is a rare but important complication of cataract surgery. We systematically reviewed the literature on previous intravitreal injections as a risk factor of PCR and performed meta‐analyses to provide pooled summary risk estimates. Methods We searched 13 literature databases on 1 June 2021 for studies evaluating the risk of PCR in eyes undergoing cataract surgery with data on previous intravitreal injections. Data extraction was made independently by two authors and discussed afterwards until reaching consensus. Random effects meta‐analyses on the pooled odds ratio (OR) of PCR in eyes with previous intravitreal injections were made using MetaXL 5.3. Results Six studies on 1 051 097 eyes undergoing cataract surgery were eligible for the qualitative and quantitative review. Previous history of intravitreal injections was present in 7034 eyes (majority was anti‐VEGF). Our meta‐analyses revealed that any previous intravitreal injection was a risk factor for PCR with an OR of 2.30 (95% CI 1.39–3.81). For each previous intravitreal injection, the risk of PCR was OR 1.04 (95% CI 1.01–1.08) (equivalent of relative risk ~1.04). In other words, risk of PCR increases by 4% for each previous intravitreal injection. Conclusions Previous intravitreal injection is a risk factor for PCR and should be taken into account when planning cataract surgery. However, to be regarded as a clinically significant risk of PCR, a substantial number of previous intravitreal injection (e.g. ≥10) should have been administered, considering that the a priori risk of PCR is very low (~1%).

show abstract

Section: Introductionmentioning

confidence: 99%

“…2016). Intravitreal injections with anti‐VEGF or corticosteroids have drastically improved visual outcomes in patients with various exudative retinal diseases (Bloch & Larsen 2015). Mean age of patients receiving intravitreal injections is reported to be at approximately 70 years in many developed countries (Schmidt‐Erfurth et al.…”

Section: Introductionmentioning

confidence: 99%

Previous intravitreal injection as a risk factor of posterior capsule rupture in cataract surgery: a systematic review and meta‐analysis

Bjerager

Dijk

Holm

et al. 2022

Acta Ophthalmologica

View full text Add to dashboard Cite

show abstract

“…Consideration could also be given to training senior ophthalmic nurses in giving intravitreal injections, as this is now practiced as a means of meeting the demands of repeat treatment of age related macular degeneration in high-income settings. [ 9 10 ] Facilities for surgical treatment of complex cases were available in almost two thirds of the eye units, with three quarters of teaching hospitals being able to provide this level of care. Overall, there was a lower need for training ophthalmologists in VR surgery which may reflect the fact that some facilities were relatively small.…”

Section: Discussionmentioning

confidence: 99%

Eye care infrastructure and human resources for managing diabetic retinopathy in India: The India 11-city 9-state study

Gilbert

Babu

Gudlavalleti

et al. 2016

Indian J Endocr Metab

View full text Add to dashboard Cite

Background:There is a paucity of information on the availability of services for diagnosis and management of diabetic retinopathy (DR) in India.Objectives:The study was undertaken to document existing healthcare infrastructure and practice patterns for managing DR.Methods:This cross-sectional study was conducted in 11 cities and included public and private eye care providers. Both multispecialty and stand-alone eye care facilities were included. Information was collected on the processes used in all steps of the program, from how diabetics were identified for screening through to policies about follow-up after treatment by administering a semistructured questionnaire and by using observational checklists.Results:A total of 86 eye units were included (31.4% multispecialty hospitals; 68.6% stand-alone clinics). The availability of a dedicated retina unit was reported by 68.6% (59) facilities. The mean number of outpatient consultations per year was 45,909 per responding facility, with nearly half being new registrations. A mean of 631 persons with sight-threatening-DR (ST-DR) were registered per year per facility. The commonest treatment for ST-DR was laser photocoagulation. Only 58% of the facilities reported having a full-time retina specialist on their rolls. More than half the eye care facilities (47; 54.6%) reported that their ophthalmologists would like further training in retina. Half (51.6%) of the facilities stated that they needed laser or surgical equipment. About 46.5% of the hospitals had a system to track patients needing treatment or for follow-up.Conclusions:The study highlighted existing gaps in service provision at eye care facilities in India.

show abstract

“…Anti-VEGF and steroid injections can be given either in theater or in a dedicated clean room that meets international and local infection control guidelines [92][93][94]. The clean room should be separated from the examination room, adequately equipped, and approved by the appropriate hospital teams (microbiology/ infection control/health and safety).…”

Section: Injection Room and International And Local Infection Controlmentioning

confidence: 99%

Management of Diabetic Macular Edema: Guidelines from the Emirates Society of Ophthalmology

Qassimi

Kozák²,

Karam³

et al. 2022

Ophthalmol Ther

View full text Add to dashboard Cite

In the United Arab Emirates, retinopathy has been shown to be present in 19% of the diabetic population, with diabetes identified in up to 40% of individuals aged over 55 years. Despite the prevalence of diabetic retinal diseases, there are no unified national guidelines on the management of diabetic macular edema (DME). These published guidelines are based on evidence taken from the literature and published trials of therapies, and consensus opinion of a representative expert panel with an interest in this condition, convened by the Emirates Society of Ophthalmology. The aim is to provide evidence-based, clinical guidance for the best

show abstract

Translational public health care perspective: Intravitreal treatment of neovascular age‐related macular degeneration has revolutionized clinical ophthalmology

Abstract: EditorialTranslational public health care perspective: Intravitreal treatment of neovascular age-related macular degeneration has revolutionized clinical ophthalmology

Cited by 6 publications

References 18 publications

Previous intravitreal injection as a risk factor of posterior capsule rupture in cataract surgery: a systematic review and meta‐analysis

Previous intravitreal injection as a risk factor of posterior capsule rupture in cataract surgery: a systematic review and meta‐analysis

Eye care infrastructure and human resources for managing diabetic retinopathy in India: The India 11-city 9-state study

Management of Diabetic Macular Edema: Guidelines from the Emirates Society of Ophthalmology

Contact Info

Product

Resources

About