Translational approaches to the neurobiological study of conditional discrimination and inhibition: Implications for psychiatric disease.
Susan Sangha,
Jacklynn M. Fitzgerald
Abstract:There is a growing number of studies investigating discriminatory fear conditioning and conditioned inhibition of fear to assess safety learning, in addition to extinction of cued fear. Despite all of these paradigms resulting in a reduction in fear expression, there are nuanced differences among them, which could be mediated through distinct behavioral and neural mechanisms. These differences could impact how we approach potential treatment options in clinical disorders with dysregulated fear responses. The o… Show more
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