“…In line with this, OCD models that show a combination of the critical face, predictive and construct validities (Korff and Harvey, 2006; Wang et al, 2009; Fineberg et al, 2011; Albelda and Joel, 2012b) predominantly mirror the compulsive acts of OCD patients. This applies for models based on spontaneous behavior [ethological models, e.g., compulsive dogs, (Vermeire et al, 2012)], behavioral models [e.g., compulsive lever-pressing during signal attenuation in rats (Joel, 2006)], pharmacological models [e.g., quinpirole-induced checking in rats (Szechtman et al, 1998)], and transgenic models [e.g., compulsive grooming in Sapap3-mutant mice, (Welch et al, 2007)].…”