Abstract:αs2‐casein mRNA (csn1s2) is translated at 25% of the efficiency of β‐casein transcripts (csn2); however, the molecular mechanisms governing the difference are unknown. The main objective of this study was to identify molecular mechanisms that explain differential translational regulation between bovine β‐ and αs2‐ casein by assessing the role of putative translational regulatory factors in both cellular and cell‐free translation systems. Sequence analysis indicated that the two transcripts share similar primar… Show more
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