Translation and validation of European Organization for Research and Treatment for Cancer quality of life questionnaire-OV-28 module into Indian languages (Hindi and Marathi) to study quality of life of ovarian cancer patients from a tertiary care cancer center

Abstract

Aim:The aim is to translate and validate the European Organization for Research and Treatment for Cancer (EORTC) ovarian cancer (OC) module (OV-28) into Hindi and Marathi to use for patients and scientific community.Methods and Results:The EORTC OV-28 was translated into Hindi and Marathi languages using prescribed guidelines by the EORTC. The process included forward translation by four translators (2 each for Hindi and Marathi). The questionnaires obtained were then given to independent backward-translators who then translated them back into English. These 2 questionnaires were then compared with the original EORTC questionnaire and the second intermediate questionnaires were formed. The second intermediate questionnaire was subsequently administered in twenty patients (10 each for Hindi and Marathi) diagnosed with OC who had never seen the questionnaire before, for pilot testing. Each of these ten patients after filling up the questionnaire themselves was then interviewed for any difficulty encountered during the filling up of the questionnaires. These were in the form of specific modules including difficulty in answering, confusion while answering, and difficulty to understand, whether the questions were upsetting and if patients would have asked the question in any different way. The suggestions were incorporated into the second intermediate questionnaires to form the final Hindi and Marathi ON-28 questionnaires. These questionnaires were then sent to the EORTC for the final approval to be used in clinical studies.Conclusion:We have successfully translated EORTC OV-28 module into Hindi and Marathi languages, and EORTC approved them to be used in clinical practice and studies for OC patients.

Validation of the Turkish version of European Organization for Research and Treatment of Cancer QLQ-OV28 ovarian cancer specific quality of life questionnaire

“…It should also be noted that in another randomized ovarian cancer study, the EORTC QLQ-OV28 module was designed without the use of these sexual function items (13) . Bajpai et al (14) also showed due to cultural taboos prevalent in India, people feel uncomfortable in talking about sexual behavior in general and a similar observation was noted when patients were asked to respond to question numbers 55-58 in the study of validation of EORTC QLQ-OV28 into Indian languages. The inconsistency of these items with the module has led to the placement of this subscale at the end of the module, so that it could be omitted without interfering with the other presented items.…”

Application of Data Mining Methods in Internet of Things Technology for the Translation Systems in Traditional Ethnic Books

“…Confusion index is the most commonly used measure to evaluate a M.T. [25]. It is the probability of test data calculated according to the language model.…”