Translation and cross-cultural adaptation of the Cornell Assessment of Pediatric Delirium scale for the Portuguese language

Abstract

ObjectiveThis study sought to translate the Cornell Assessment of Pediatric Delirium from English into Brazilian Portuguese and cross-culturally adapt it for use in Brazil.MethodsFollowing the authorization granted by its main author, the processes of translation and cross-cultural adaptation were performed with regard to the Cornell Assessment of Pediatric Delirium in accordance with the following internationally recommended steps: translation of the original into Portuguese by two native speakers of the target language; synthesis of the translated versions; back-translation by two native speakers of the original language; review and harmonization of the back-translation; a review of the Portuguese version of the Cornell Assessment of Pediatric Delirium by an expert panel composed of specialists; pretesting including assessments of clarity, comprehensibility, and acceptability of the translated version using a sample of the target population; and finishing modifications to achieve the final version.ResultsThe translation and cross-cultural adaptation of the Cornell Assessment of Pediatric Delirium followed international recommendations. The linguistic and semantic issues that emerged during the process were discussed by the expert panel, which unanimously agreed to slight modifications. During pretesting, the Cornell Assessment of Pediatric Delirium was administered to 30 eligible children, twice per day; the final version was easy to understand, could be completed quickly, and showed a high inter-rater correlation coefficient (0.955).ConclusionsThe translation of the Cornell Assessment of Pediatric Delirium into Brazilian Portuguese and its cross-cultural adaptation were successful and preserved the linguistic and semantic properties of the original instrument. The Cornell Assessment of Pediatric Delirium proved to be easy to understand and could be completed quickly. Additional studies are needed to test the validity and psychometric properties of this version in Brazil.

Immune Effector Cell Associated Neurotoxicity (ICANS) in Pediatric and Young Adult Patients Following Chimeric Antigen Receptor (CAR) T-Cell Therapy: Can We Optimize Early Diagnosis?

“…CAPD has been validated as a tool for detection of delirium in critically ill and/or younger oncology patients (14,25,26). The tool has also been successfully implemented across different cultures and in different languages (27)(28)(29). An earlier report, suggests that the CAPD is a sensitive screen for ICANS among patients with relapsed or refractory B-ALL who were enrolled in phase I of an open label phase I/II clinical trial (clinicaltrials.gov NCT02028455) of CD19-directed, 4-1BB costimulated CAR T-cells (SCRI-CAR19v1) (30).…”

Delirium in a Tertiary Pediatric Cardiac Intensive Care Unit: Risk Factors and Outcomes

“…The CAPD is validated in children of all ages, with high sensitivity (94%) and acceptable specificity (79%). 14,[17][18][19][20][21][22][23] We queried the EMR to identify all children admitted to the CICU from 3/1/2014-10/1/2016, restricted to the first CICU admission in this period. We excluded patients who never received mechanical ventilation due to a care limitation order and those who had no recorded CAPD scores.…”

Cross-cultural adaptation of the Richmond Agitation-Sedation Scale to Brazilian Portuguese for the evaluation of sedation in pediatric intensive care

“…In addition to being easy to use, it has been shown to have excellent interobserver reliability in adults admitted to clinical and surgical ICUs and excellent validity when compared to the VAS and other selected sedation scales (Glasgow Coma Scale, Ramsay and SAS). ( 23 , 27 ) It has been widely used not only to grade the level of sedation or agitation for monitoring and therapeutic adjustment but also as a prerequisite for the application of other instruments, such as the Pediatric Confusion Assessment Method for the Intensive Care Unit (pCAM-ICU) ( 44 ) and the Cornell Assessment of Pediatric Delirium, ( 45 ) both of which have been adapted for Brazilian Portuguese, ( 46 , 47 ) the Preschool Confusion Assessment Method for the ICU (psCAM-ICU) ( 48 ) and the Sophia Observation Withdrawal Symptoms scale-Pediatric Delirium scale (SOS-PD). ( 49 ) The RASS has undergone cross-cultural adaptation for other languages, such as Swedish, Spanish and Serbian.…”