Transitional cell carcinoma of the bladder with parotid metastasis: a case report

Abstract

Transitional cell carcinoma (TCC) of the bladder is the most common urothelial malignancy. Sites of metastatic spread are usually predictable; typically the pelvic and para-aortic lymphatics, followed by extra-vesical tissues, i.e. liver, lung, bone and adrenal glands. There is currently little literature describing metastatic spread to the head and neck region, and none to the authors’ knowledge, of spread to the parotid salivary glands. This report describes a rare case of parotid metastasis of bladder TCC in a 75-year-old Caucasian woman.

Nested variant of urothelial carcinoma metastatic to the parotid gland

“…We have presented a very rare example of a parotid metastasis of a UC. Kitchen et al 2 To the best of our knowledge, this is the first report to demonstrate cytomorphological features of NVUC in FNA material. Although the occurrence of uniform, bland-looking tumour cells and lack of significant atypia were misleading features, previously described cytological characteristics of UC (prominent nucleoli, nuclear grooves, cytoplasmic tails) were present, at least focally in our case.…”

“…Kitchen et al. previously published the first case of metastatic UC to the parotid gland. In their report, the patient had a poorly differentiated UC (pT3) in the bladder.…”

“…We could find only two cases of parotid metastasis from urothelial carcinoma (UC) of the bladder published in the English literature. 2,3 Here, we present an example of a nested variant of UC (NVUC) metastasis to the parotid with welldocumented cyto-and histomorphological features.…”

“…Parotid gland metastasis from UC of the bladder is extremely rare . Detailed clinicopathological features of these reported cases are summarised in the Table .…”