Transitional cell carcinoma arising in a pyelocaliceal cyst

Abstract

The differentiation between benign and malignant cystic lesions of the kidney is a diagnostic challenge. Medical imaging aids in this task, but many cystic renal lesions require further work-up, frequently by computed tomography-guided fine needle aspiration. We report on the pathological findings in a case of moderately differentiated papillary transitional carcinoma, which arose in a pre-existing pyelocaliceal cyst in a 53-year-old man. In the case of this lesion, the distinction between a benign and a malignant renal cyst is blurred. To our knowledge, this is the third such occurrence to be reported and the first to be diagnosed by fine needle aspiration biopsy.

Transitional cell carcinoma arising in a calyceal cyst mimicking a cystic renal tumour

“…9 Roberts and colleagues also performed nephroureterectomy of the rest of the ureter when TCC was identified in a frozen section tissue biopsy conducted during surgery. 10 In the present case, the patient's condition was diagnosed as cystic RCC, on the basis of pre-surgical CT scans.…”

Carcinoma Uroteliale in Cisti Pielogena

“…Rari sono i casi riportati in letteratura di carcinoma uroteliale in cisti pielogena (5–7) e nessuno di quelli riportati ha un'iconografia RM. Nel caso clinico da noi riportato abbiamo optato per un intervento di nefrectomia poiché la lesione era mesorenale, con diametro massimo di 69 mm, ed era stata responsabile di macroematuria lateralizzata.…”

“…La presenza di neoplasia all'interno delle cisti pielogene è stata riportata raramente nella letteratura scientifica (5–7) e le neoplasie uroteliali in cisti pielogene non rientrano tra le patologie comunemente sospettate allorquando ci si trovi di fronte ad una cisti complex.…”