Transition‐Metal‐Catalyzed Carbonylative Domino Reactions

Palladium-catalyzed decarboxylation [2 + 2 + 2] annulation approach to chromone-containing polycyclic compounds

“…3 Transition metal-catalyzed domino reaction has been proven as an effective approach to assemble complex molecules by forging two or more new chemical bonds from readily available substrates in one single operation. 4 In this context, the Catellani-type annulation cooperatively catalyzed by palladium and norbornene (NBE) represents a powerful tool for the construction of complex arenes. In 2000, Lautens pioneeringly reported a Pd/NBE catalyzed sequential aromatic substitution and intramolecular Heck reaction of iodoaryl compounds to give six- and seven-membered-ring carbocycles.…”

Chemodivergent and Diastereoselective Synthesis of γ-Lactones and γ-Lactams: A Heterogeneous Palladium-Catalyzed Oxidative Tandem Process

“…Despite the elegant work on ligand- and solvent-controlled chemoselective carbonylative reactions developed in homogeneous systems, , to date, there are no reports on catalyst-controlled chemo- and diastereoselective carbonylations achieved with heterogeneous palladium catalysts. As a result of its high surface area (500–800 m 2 g –1 ) and large pore sizes (∼26 nm), amino-functionalized mesocellular foam (AmP-MCF) could act as an ideal support for Pd and an excellent host for CO gas .…”