Transition-Metal-Catalyzed C–H Activation Reactions for the Creation and Modification of Organic Fluorophores

Abstract

Organic fluorophores have consistently garnered significant interest owing to their widespread application across various multidisciplinary research fields. In the realm of biological research, these organic fluorophores find extensive use in diverse applications such as molecular imaging, DNA sequencing, drug discovery, and biosensors. Remarkably, in recent times, organic fluorescent molecules have emerged as pivotal elements in the advancement of organic electronics. Across the several reaction pathways developed for constructing and modifying organic fluorophores, transition metal-catalyzed C-H activation reactions have come across as a dependable and step-economical approach. In this review we discuss various transition metal-catalyzed C-H activation-based approaches which have been employed to create and modify organic fluorescent molecules which find applications in multidisciplinary research areas.