Transient splenial lesion of corpus callosum: A window to many diagnoses

Abstract

Transient splenial lesions (TSL) are not of frequent occurrence and are usually observed with other diseases. The mechanism of TSL development still unclear despite of various theories put forward. These are secondary lesions and their diagnosis is of importance to associate them with clinical conditions. Magnetic resonance imaging is the modality of diagnosing TSL and 3T MRI was used in this study. The study includes 10 cases of TSL with varied disease etiologies like migraine, trauma, infection, demyelination etc. All the cases had follow-up imaging which showed resolution of the lesions after varied time intervals. An attempt to correlate the various theories with each type of disease is done in this study.

Lesson of the month: Cytotoxic lesions of the corpus callosum (CLOCCs) in status epilepticus

“…Without follow-up imaging, such lesions cannot be termed as CLOCCs. 8 Infarctions can be one of the causes of such lesions, but infarctions restricted to the CC are rare because of its rich blood supply from the different arteries bilaterally. Furthermore, the perpendicular orientation of the callosal branches may prevent embolisation.…”