Transient Pseudohypoaldosteronism in an Infant: A Case Report

Abstract

Transient pseudohypoaldosteronism is strongly linked to urinary tract infections complicating structural urinary tract anomalies. A 3-month-old baby girl with hyponatremia, hyperkalemia and metabolic acidosis associated with urinary tract infection and structural urinary tract anomalies was diagnosed with transient pseudohypoaldosteronism following elevated serum aldosterone and normal 17-hydroxyprogesterone level. Electrolytes normalized with corrections and antibiotic therapy. Clinicians should have a high index of suspicion for transient pseudohypoaldosteronism in an infant presenting with hyponatremia, hyperkalemia and urinary tract infection with or without associated urinary tract anomalies.

Severe Hyponatremia in a 6-month-old Infant

“…We want to congratulate Latt and colleagues on the article describing a case of a patient with transient pseudohypoaldosteronism. 1 Electrolyte derangements in course of this rare entity may be much more severe, as in our patient presenting with hyponatremia of 103 mmol/L. We feel that we can contribute to the topic by reporting our patient and discussing hyponatremia management.…”