Transient otoacoustic emissions in children with chronic renal failure

Abstract

This study was conducted on 34 children with chronic renal failure: 27 on regular haemodialysis and seven on conservative treatment. Twenty normal healthy children served as controls. They were subjected to clinical examination including otoscopic examination, basic audiological assessment and transient otoacoustic emission testing (TOAE). Four patients had a conductive hearing loss and five had a bilateral moderately severe high frequency sensory neural hearing loss. TOAE testing was carried out for the rest whose ears displayed normal hearing. No response (fail) was obtained in 8% of them but in none of the controls and a partial pass response in 38% versus 10% of controls (P < 0.001). Cochlear dysfunction was significant only at low frequency levels. The mean overall echo-level and reproducibility were significantly lower in patients than in controls. The same holds true for the subgroup of patients on haemodialysis but not for those on conservative treatment. The overall echo-levels did not correlate with serum urea, creatinine, sodium or potassium.

Auditory brain stem response and otoacoustic emission results in children with end-stage renal disease

“…Twenty normal healthy children served as controls. OAE testing was failed in 11.1% of patients on HD but in none of the patients on conservative [11,12,16,17,21]. Our results are also in the reported ranges.…”

“…Sensorineural hearing loss was found in 30.4% of their patients. Samir et al [21] studied 34 children with CRF; 27 on regular HD and 7 on conservative treatment. Twenty normal healthy children served as controls.…”

Risk of sudden sensorineural hearing loss in patients with end‐stage renal disease undergoing dialysis

“…In addition, uremic neuropathy may contribute to auditory dysfunction . Studies on brain‐evoked response audiometry and otoacoustic emissions tests show that cochlear or retrocochlear origins of hearing loss are common in patients with ESRD . This is particularly common in children with dialysis …”

Prevalence and patterns of hearing loss among chronic kidney disease patients undergoing haemodialysis

“…[4][5][6] Haemodialysis has also been reported to contribute to hearing loss in CKD. 7 Studies on the impact of haemodialysis have produced contradictory results, with a sizeable number reporting that haemodialysis plays no role in hearing loss associated with CKD. Although chronicity of disease was found to have no association with hearing loss in many studies, 8 a recent study demonstrated that the greater the duration of disease, the greater the hearing loss.…”