Transient osteoporosis of the hip in pregnancy – a case series

The correlation between transient osteoporosis of the hip and pregnancy: A review

“…[34] A previous publication from Hadji P. et al revealed that women with TOH demonstrated a 2 kg bigger mean body weight contrasted to females without TOH, [26] which is supportive of the mechanical theory. Nevertheless, these findings are conflicting with the study of Toussia-Cohen S. et al, [32] which delineated that women BMIs, both prior-pregnancy and at childbirth (22.03 and 27.6, correspondingly), are comparatively small contrasted to average BMI figures in the population (24.7 and 29.7, correspondingly). Papers concerning non-transient osteoporosis have deduced that increased BMI ameliorates BMD, ergo reducing fracture danger, whilst small-scale BMI is a well-recorded risk factor for osteoporotic fractures.…”

“…[30] In particular, TOH can be misdiagnosed as simple sciatica or sacroiliac strain. [31] The most contemporary research concerning females diagnosed with TOH at a sole hospital was conducted by Toussia-Cohen S. et al [32] In this study, both obstetric and clinical features and findings of 34 pregnant females identified with TOH during gestation or postnatal period were reported and analyzed. [32] The utmost findings of this study included: a comparatively increased maternal age (average age of mothers was 34.18 ± 4.75 years), the conspicuous preponderance of family history of non-PAO (29.4%) and escalated smoking proportions (47.1%), as well as women low prior-pregnancy body mass index (BMI) and at childbirth (22.03 and 27.60, correspondingly).…”

“…What more, 2 women (13.3%) were reported with TOH in a sequential gestation. [32] Regarding maternal age at the time of TOH diagnosis, in the review paper by Quaresima et al, [25] average mothers age was 32.10 ± 5.50 years. Notwithstanding, Hadji et al [26] reported 33 pregnant females identified with TOH in which the average age was found 35.20 ± 4.10 years.…”

“…This finding was ascribed to the cumulated familiarity with TOH patients, in addition to enhanced magnetic resonance imaging (MRI) scan availability that offers physicians the reassurance to permit pregnant females with TOH to attempt delivering vaginally. [32] Concerning diagnosis timing, physicians ought to be tremendously aware of groin pain in the postnatal period, chiefly taking into account that medical monitoring at this period is patently limited than during gestation, considering carrying out an MRI scan in cases of acute persistent pain.…”

“…Eventually, all except for one case healed with no subsequent necrosis, irrespective of the time elapsed since the fracture was discerned. [57] The cohort study by Toussia-Cohen S. et al [32] inquired into the results of LMWH usage for a limited period (3-6 months), inferring that LMWH, as used in the research, is not expected to expose pregnant patients to an increased fracture danger. Nonetheless, if LMWH treatment is projected for an expanded period, advantages and disadvantages should be gingerly assessed before treatment commencement.…”