Transient Osteoporosis

Korompilias, Anastasios V.; Karantanas, Apostolos H.; Lykissas, Marios G.; Beris, Alexandros E.

doi:10.5435/00124635-200808000-00007

Cited by 63 publications

(81 citation statements)

References 42 publications

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“…High-turnover osteoporosis is the most common form and occurs in postmenopausal women (so-called primary type-I osteoporosis) or in patients with hyperparathyroidism regardless of their menopausal state 48 . Transient osteoporosis, most commonly seen in men, is also a high-turnover state 49 . Lowturnover osteoporosis occurs in the elderly (so-called age-related osteoporosis, or primary type-II osteoporosis) or following drug interventions, including chemotherapy, corticosteroids, and prolonged bisphosphonate treatment 47,50,51 .…”

Section: Assessment Of Bone Turnovermentioning

confidence: 99%

The Assessment of Fracture Risk

Unnanuntana

Gladnick

Donnelly

et al. 2010

The Journal of Bone and Joint Surgery-American Volume

300

207

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Bone mineral density is considered to be the standard measure for the diagnosis of osteoporosis and the assessment of fracture risk. The majority of fragility fractures occur in patients with bone mineral density in the osteopenic range.ä The Fracture Risk Assessment Tool (FRAX) can be used as an assessment modality for the prediction of fractures on the basis of clinical risk factors, with or without the use of femoral neck bone mineral density. Treatment of osteoporosis should be considered for patients with low bone mineral density (a T-score of between 21.0 and 22.5) as well as a ten-year risk of hip fracture of ‡3% or a ten-year risk of a major osteoporosis-related fracture of ‡20% as assessed with the FRAX.ä Biochemical bone markers are useful for monitoring the efficacy of antiresorptive or anabolic therapy and may aid in identifying patients who have a high risk of fracture.ä An approach combining the assessment of bone mineral density, clinical risk factors for fracture with use of the FRAX, and bone turnover markers will improve the prediction of fracture risk and enhance the evaluation of patients with osteoporosis.

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Section: Assessment Of Bone Turnovermentioning

confidence: 99%

The Assessment of Fracture Risk

Unnanuntana

Gladnick

Donnelly

et al. 2010

The Journal of Bone and Joint Surgery-American Volume

300

207

View full text Add to dashboard Cite

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“…The characteristic MRI finding is widespread marrow edema throughout the proximal femur including femoral head, neck, and trochanteric region, whereas ON is usually located focally in the femoral head or subchondral region. Plain radiographs are frequently unremarkable except relative osteopenia [51][52][53]. A bone scan shows marked, diffuse increased uptake throughout the entire femoral head and neck region.…”

Section: Bone Scanmentioning

confidence: 99%

Osteonecrosis of the femoral head: diagnosis and classification systems

Choi

Steinberg

Cheng

2015

Curr Rev Musculoskelet Med

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Osteonecrosis of femoral head is a rare but disabling condition that usually results in progressive femoral head collapse and secondary arthritis necessitating total hip arthroplasty if not treated appropriately in early stages. However, early diagnosis is challenging as the onset of disease is insidious and the symptoms and signs are usually minimal and nonspecific until it becomes advanced. Of several diagnostic modalities, magnetic resonance imaging (MRI) is considered the imaging method of choice with the highest sensitivity and specificity, while detection of potential risk factors is very important as well. Many investigators have developed several different classification systems; however, there still is controversy regarding the optimal classification system. Diagnostic methods and the evolution of different classification systems will be reviewed in this paper.

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“…10 The exact aetiology is unknown; chemical, hormonal, mechanical, genetic, viral infection, and neurovascular theories have been proposed. 5,7,20 The most accepted mechanism is microvascular injury, which leads to tissue ischaemia and then marrow oedema. 21 The course of transient osteoporosis is benign and eventually recover within 6 to 12 months.…”

mentioning

confidence: 99%

Bilateral Subcapital Femoral Neck Fractures Secondary to Transient Osteoporosis during Pregnancy: A Case Report

Emami

Abdollahpour

Kazemi

et al. 2012

J Orthop Surg (Hong Kong)

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Transient osteoporosis during pregnancy is a rare, self-limiting disease. We report on a 36-year-old woman who had bilateral subcapital femoral neck fractures during the 6th month of pregnancy. The diagnosis was made 4 days after delivery, because radiography was declined by the patient for fear of radiation. Fixation was not feasible owing to bone resorption, and 2-stage bipolar hemiarthroplasty was therefore performed. Magnetic resonance imaging is the best non-invasive investigative tool for pregnant women with hip pain. Early detection can prevent complications and resorting to major surgeries.

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Transient Osteoporosis

Cited by 63 publications

References 42 publications

The Assessment of Fracture Risk

The Assessment of Fracture Risk

Osteonecrosis of the femoral head: diagnosis and classification systems

Bilateral Subcapital Femoral Neck Fractures Secondary to Transient Osteoporosis during Pregnancy: A Case Report

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