Transient neurologic symptoms after spinal anaesthesia using isobaric 2% mepivacaine and isobaric 2% lidocaine

Salazar, F.; Bogdanovich, A; Adàlia, R.; Chabás, E; Gomar, C.

doi:10.1034/j.1399-6576.2001.450216.x

Cited by 62 publications

(33 citation statements)

References 38 publications

(62 reference statements)

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“…31 Results from smaller randomized blinded trials have demonstrated rates of TNS ranging from 0 to 7.4%. 10,18,32,33 Reported risk factors for the development of TNS include outpatient status, obesity, lithotomy, and knee arthroscopy position. 34,35 In the present study, no patient reported symptoms consistent with TNS despite some of our enrolled patients having many of the reported risk factors.…”

Section: Discussionmentioning

confidence: 99%

Mépivacaïne rachidienne additionnée de fentanyl pour une arthroscopie du genou en ambulatoire: une étude randomisée contrôlée

O’Donnell

Manickam

Perlas

et al. 2009

Can J Anesth/J Can Anesth

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Section: Discussionmentioning

confidence: 99%

Mépivacaïne rachidienne additionnée de fentanyl pour une arthroscopie du genou en ambulatoire: une étude randomisée contrôlée

O’Donnell

Manickam

Perlas

et al. 2009

Can J Anesth/J Can Anesth

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“…The study population was not large enough to discover any difference in the occurrence of rare side-effects such as TNS. After lidocaine spinal anesthesia, the reported incidence of TNS has varied from 0% to 40% [26,27]. Although the anesthetic characters are quite similar with articaine and lidocaine, TNS rate was lower in articaine than lidocaine and the Cesarean section in such a short operation may be preferred.…”

Section: Discussionmentioning

confidence: 99%

Comparison of intrathecal plain articaine and levobupivacaine with fentanyl for Caesarean section

Demircioğlu¹,

Gözdemir²,

Usta³

et al. 2016

CIM

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Purpose: Articaine is used as a local anesthetic for outpatient surgery because it offers rapid onset of anesthesia and short duration motor block. Levobupivacaine is often preferred for Caesarean section. We evaluated the anesthetic characteristics of fentanyl-supplemented plain articaine and levobupivacaine for Caesarean section under combine spinal epidural anesthesia.Methods: Patients undergoing Caesarean section received in random order plain articaine 40 mg (Group A, n=50) or plain levobupivacaine 10 mg (Group L, n=50) mixed with fentanyl 20 µg intrathecally. The onset and duration of sensory and motor block, first analgesic request, and hemodynamic parameters were recorded.Results: Onset times of maximum motor block were longer in Group L than Group A (P=0,001). Time to two-segment regression of sensory block were 70 min for Group A and 90 min group L (P=0.001). Times to complete regression of motor blockade were significantly longer in group L than group A (P =0,001). Conclusion:To have a faster onset and shorter duration of spinal anesthesia, we recommend the use of plain articaine for Caesarean section.SUPPLEMENT

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“…Postoperatif ilk günlerde görülen bu komplikasyonların insidansı, muhtemel sebepleri, risk faktörleri ve tedavisi anestezistlerin ilgi odağı haline gelmiş ve çok sayıda çalış-manın konusu olmuştur. [9][10][11] Başlarda, lidokainle spinal anestezi uygulanan hastalarda derlenme sonrası izlenen bu durum ''geçici nörolojik toksisite'' olarak adlandırılmış, [7,8] irritasyon'' [6] ve son olarak ''geçici nörolojik semptom'' [12] olarak literatüre geçmiştir.…”

Section: Discussionunclassified

Transient neurological symptoms after spinal anesthesia

Çetin¹,

Kayacan

Karsli³

2018

Agri

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SummaryObjectives: Transient neurological symptoms (TNS) after spinal anesthesia vary from dysesthesia that is hardly noticed to severe pain. The aim of this study was to determine the incidence of TNS and provocative risk factors in 591 patients who underwent central block. Methods: Before the operation, demographic data and features of the operation and the block were recorded. The patients were evaluated at postoperative 24 and 48 hours and day 7 with regard to TNS in the form of pain (headache, lower back and/or limb pain, backache, pain in the puncture region) and sensation disorders (paresthesia, hypoesthesia, hyperesthesia, anesthesia, dysesthesia). Results: The incidence of TNS among the study patients was 35.7%. It was significantly higher in gynecology and urology patients and was higher in female patients in comparison with male patients. The incidence of TNS was greater when blood in the needle/catheter, pain, or paresthesia was seen, but was not associated with LA agents used in the study. Conclusion: A similar TNS incidence was seen in the results of this study as has been reported in the literature. A greater number of attempts, the lithotomy position, and co-morbidities such as ASHD and DM increase the incidence of TNS.Keywords: Regional anesthesia; TNS; sensation disorder. ÖzetAmaç: Santral blok sonrası gözlenen GNS, hastaların zorlukla farkına varabildikleri dizesteziden, çok şiddetli ağrıya kadar oldukça değişken ve geniş şikayetler dizisini içermektedir. GNS sıklığını ve potansiyelize eden risk faktörlerinin belirlenmesini amaçlayan bu çalışmaya, santral blok uygulanan 591 hasta dahil edildi. Gereç ve Yöntem: Operasyon öncesi hastaların demografik bilgileri, operasyon ve uygulanan blok türüne ait özellikler kaydedildi. Hastalar postoperatif 24, 48 saat ve 7. günde GNS olarak ağrı (başağrısı, bel ve/veya bacak ağrısı, sırt ağrısı, girişim yeri ağrısı) ve duyu kusurları (parestezi, hipoestezi, hiperestezi, anestezi, dizestezi) açısından değerlendirildi. Bulgular: Çalışmaya katılan hastalarda GNS sıklığı, %35.7 olarak hesaplanırken, bu oran KHD, üroloji hastalarında anlamlı olarak yüksekti. GNS, kadın hastalarda erkek hastalara göre anlamlı olarak fazla bulundu. Santral blok uygulamaları sırasında iğne/ kateterden kan gelmesi, ağrı ve parestezi varlığında, GNS insidansında artma izlenirken, kullanılan LA ajanlar arasında, GNS insidansında farklılık bulunmadı. Sonuç: Çalışmamızda literatür bilgileriyle benzer GNS oranları bulduk. Artan ponksiyon sayısı, litotomi pozisyonu, eşlik eden ASKH ve DM gibi komorbid durumlar GNS insidansını artırmaktadır.Anahtar sözcükler: Duyu kusuru; GNS; rejyonal anestezi. 58NISAN -APRIL 2018

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Transient neurologic symptoms after spinal anaesthesia using isobaric 2% mepivacaine and isobaric 2% lidocaine

Abstract: In this study TNS was associated with isobaric mepivacaine 20 mg/ml, with an incidence of 7.5%, and with isobaric lidocaine 20 mg/ml, with an incidence of 2.5%, in patients having orthopaedic procedures in the supine position.

Cited by 62 publications

References 38 publications

Mépivacaïne rachidienne additionnée de fentanyl pour une arthroscopie du genou en ambulatoire: une étude randomisée contrôlée

Mépivacaïne rachidienne additionnée de fentanyl pour une arthroscopie du genou en ambulatoire: une étude randomisée contrôlée

Comparison of intrathecal plain articaine and levobupivacaine with fentanyl for Caesarean section

Transient neurological symptoms after spinal anesthesia

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