Transient intubation for surfactant administration in the treatment of respiratory distress syndrome in extremely premature infants

Koh, Ji Won; Kim, Jongwan; Chang, Young Pyo

doi:10.3345/kjp.2018.06296

Cited by 3 publications

(3 citation statements)

References 31 publications

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“…Other characteristic signs such as lung parenchyma, disappearance of the A line, presence of the B line and air-bronchogram sign may reflect early lung lesions. 14 - 16 The alveolar-air interface has surface tension. The lack of surface active substances in NRDS children leads to alveolar compression and poor alveolar ventilation.…”

Section: Discussionmentioning

confidence: 99%

Analysis of diagnosing neonatal respiratory distress syndrome with lung ultrasound score

Huang¹,

Ye²,

Wang

2022

Pak J Med Sci

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Objectives: To investigate the diagnostic effect of lung ultrasound on neonatal respiratory distress syndrome (NRDS) and to analyze the clinical application value of pulmonary ultrasound score. Methods: Sixty-five NRDS babies who were diagnosed in our hospital from August 2019 to October 2020 were selected as the observation group, and 65 healthy babies were selected as the control group. Children in the two groups underwent lung ultrasound examination. The characteristic signs of lung ultrasound in the two groups were analyzed, and the detection rate of various signs and lung ultrasound score were compared between the two groups. Results: The main manifestations of lung ultrasound in NRDS children were pulmonary parenchyma, abnormal pleural line, blurred or disappeared A line, pleural effusion, white lung, and weak or disappeared pulmonary pulsation; the lung ultrasound scores of different positions in the observation group were higher than those in the control group, and the differences were statistically significant (P<0.05). The detection rates of signs such as lung parenchyma, abnormal pleural line, disappeared A line, diffuse pulmonary edema, and air bronchogram in the observation group were significantly higher than that in the control group (P<0.05), and there was no significant difference in the detection rate of the sign of B line existence between the two groups (P>0.05). Conclusion: Lung ultrasound has a high diagnostic value in diagnosing NRDS, and lung ultrasound score can evaluate the severity of NRDS in babies to further optimize the diagnosis results, which has important clinical significance. doi: https://doi.org/10.12669/pjms.38.5.5202 How to cite this:Huang L, Ye D, Wang J. Analysis of diagnosing neonatal respiratory distress syndrome with lung ultrasound score. Pak J Med Sci. 2022;38(5):---------. doi: https://doi.org/10.12669/pjms.38.5.5202 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Section: Discussionmentioning

confidence: 99%

Analysis of diagnosing neonatal respiratory distress syndrome with lung ultrasound score

Huang¹,

Ye²,

Wang

2022

Pak J Med Sci

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“…In Korea, some studies have suggested that the early application of CPAP for RDS treatment is effective and can reduce the occurrence of lung injury via the Intubate-SURfactant-Extubation technique. However, there has been little research on LISA 4142…”

Section: The History Of Ps In Koreamentioning

confidence: 99%

History of Pulmonary Surfactant Replacement Therapy for Neonatal Respiratory Distress Syndrome in Korea

et al. 2019

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Neonatal respiratory distress syndrome (RDS) is a disease that is unique to newborn infants. It is caused by a deficiency of pulmonary surfactant (PS), which is usually ready to be activated around the perinatal period. Until RDS was more clearly understood, it was not known why premature infants died from respiratory failure, although pathology revealed hyaline membranes in the alveoli. Surprisingly, the era of PS replacement therapy began only relatively recently. The first clinical trial investigating neonatal RDS was conducted in 1980. Since then, newborn survival has improved dramatically, which has led to significant advances in the field of neonatology. The present comprehensive review addresses PS, from its discovery to the application of artificial PS in newborns with RDS. It also reviews the history of PS in Korea, including its introduction, various commercial products, present and past research, newborn registries, and health insurance issues. Finally, it describes the inception of the Korean Society of Neonatology and future directions of research and treatment.

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“…The first neonatal intensive care unit was established in the United States in 1965 at the Yale University School of Medicine. In 1980, exogenous surfactant was used for the first time in the treatment of respiratory distress syndrome [ 3 , 4 ]. The next advance in perinatal medicine was the antenatal use of steroids, following the 1994 New York Declaration [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Complications of Preterm Birth—The Importance of Care for the Outcome: A Narrative Review

Zivaljevic,

Jovandaric,

Babic

et al. 2024

Medicina

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Preterm-born children are susceptible to problems of adaptation in the early neonatal period, as well as the emergence of consequences due to the immaturity of the respiratory, cardiovascular, and especially cerebrovascular systems. The authors searched PubMed, Scopus, the Cochrane Library, and Web of Science for articles that were available in their entirety and published in English between 1990 and 2024 in peer-reviewed journals using keywords relevant to the manuscript topic. Analyzing the requested studies and manuscripts, adequate articles describing the stated problem were used. The last trimester of pregnancy is the most important period in brain development. Brain growth is at its most intense, and nerve cells are created, multiply, and migrate, creating numerous connections between them and receptors. During this period, the baby is protected from the influence of external environmental factors. When a baby is born, it leaves its protected environment and very often requires intensive treatment to survive. In these circumstances, the immature nervous system, which is in a sensitive stage of development, is overloaded with numerous external stimuli, continuous light, noise, inappropriate positioning, and repeated painful reactions due to necessary diagnostic and therapeutic procedures and the unavoidable absence of the mother and the family, which cause stress that threatens proper programmed development. Minimally invasive therapeutic procedures and the presence of parents during hospitalization play a significant role in reducing the consequences for a premature child.

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Transient intubation for surfactant administration in the treatment of respiratory distress syndrome in extremely premature infants

Cited by 3 publications

References 31 publications

Analysis of diagnosing neonatal respiratory distress syndrome with lung ultrasound score

Analysis of diagnosing neonatal respiratory distress syndrome with lung ultrasound score

History of Pulmonary Surfactant Replacement Therapy for Neonatal Respiratory Distress Syndrome in Korea

Complications of Preterm Birth—The Importance of Care for the Outcome: A Narrative Review

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