Transient elastography for diagnosis of stages of hepatic fibrosis and cirrhosis in people with alcoholic liver disease

Pavlov, Chavdar S; Casazza, Giovanni; Nikolova, Dimitrinka; Tsochatzis, Emmanuel; Burroughs, Andrew K.; Vt, Ivashkin; Gluud, Christian

doi:10.1002/14651858.cd010542.pub2

Cited by 81 publications

(67 citation statements)

References 95 publications

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“…In this study with 330 participants it has been found that sensitivity and specificity of transient elastography were 0.95 and 0.71 with LR+ 3.3 and LR-0.07. The study has concluded that transient elastography could be a reliable and useful physical method to be used as an alternative liver biopsy [39].…”

Section: Assessment Of Liver Fibrosismentioning

confidence: 97%

“…This novel non-invasive method has been designed for assessment of hepatic fibrosis in patients with chronic liver diseases [39]. However, its validity could highly be increased if combined with other no-invasive devices including serum markers.…”

Section: Assessment Of Liver Fibrosismentioning

confidence: 99%

“…The diagnostic accuracy of transient elastography for diagnosis and staging hepatic fibrosis has been compared to liver biopsy in people with alcoholic liver disease [39]. A number of 834 studies were reviewed to provide data for analyses.…”

Section: Assessment Of Liver Fibrosismentioning

confidence: 99%

See 2 more Smart Citations

Liver Fibrosis: Causes and Methods of Assessment, A Review

Toosi

2015

Romanian Journal of Internal Medicine

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Hepatic fibrogenesis is the final result of injury to the liver. Fibrosis could lead to hepatic dysfunction, important in the pathogenesis of other chronic problems. Therefore, understanding the mechanism, accurate diagnosis and staging of it in early stages accelerates the treatment and reduces the prevalence of chirrosis. Treatment strategies of liver problems and detction methods depend on the amount and progression of liver fibrosis and the rate of cirrhosis development. Traditionally the invasive method, liver biopsy, is reference standard to follow progression and stage of fibrosis. However, during the past decade, progressive development of novel non-invasive methodologies has challenged the invasive method. Non-invasive methods have been initially introduced for chronic hepatitis C with increasing use in other chronic liver diseases. The need for liver biopsy has nowadays decreased significantly as a result of these methodologies. Most of the new non-invasive methods depend on either 'biological' or 'physical' approaches.In this review, starting from the mechanism of fibrogenesis, the current knowledge about diagnosis, treatment strategies and different methods for its evaluation is discussed. This is followed by a conclusion on what is expected to be known in this field during the future research.

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Section: Assessment Of Liver Fibrosismentioning

confidence: 97%

Section: Assessment Of Liver Fibrosismentioning

confidence: 99%

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Liver Fibrosis: Causes and Methods of Assessment, A Review

Toosi

2015

Romanian Journal of Internal Medicine

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“…At a Young's modulus of 12.5 kPa, TE may rule out cirrhosis with a negative likelihood ratio of 0.07 if the disease prevalence is 50 % or lower. [214].…”

Section: Prediction Of Liver-related Complicationsmentioning

confidence: 99%

Untitled

2017

Ultraschall in Med

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“…The probe is separate from an ultrasound probe, and requires a vessel-free area for proper measurement [117]. A recent meta-analysis of TE use in alcoholic-related disease and LC diagnosis, TE could be useful in ruling out the presence of significant fibrosis, thus possibly avoiding a liver biopsy depending on clinical reasoning, and more applicable screening method to the surgical patient [118].…”

Section: Fibroscanmentioning

confidence: 99%

Perioperative Risk Assessment and Management of Cirrhotic Patients

AL¹,

Dong²,

Nayi³

2015

J Hepatol Gastroint Dis

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Liver cirrhosis is an important risk factor for morbidity and mortality in any type of surgical procedure. For these patients, a distinct and tailored patient optimization approach prior to surgery is required in order to best risk mitigate towards avoiding decompensation and related complications, especially with the chronicity of this disease. This review is to enhance understanding of surgical risks in these patients in selecting patients for elective surgery, or managing those following emergency surgery.

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Transient elastography for diagnosis of stages of hepatic fibrosis and cirrhosis in people with alcoholic liver disease

Abstract: Transient elastography for diagnosis of stages of hepatic fibrosis and cirrhosis in people with alcoholic liver disease (Review)

Cited by 81 publications

References 95 publications

Liver Fibrosis: Causes and Methods of Assessment, A Review

Liver Fibrosis: Causes and Methods of Assessment, A Review

Untitled

Perioperative Risk Assessment and Management of Cirrhotic Patients

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