“…However, till now, we still mainly depend on liver biopsies to assess their disease status, including the degree of liver fibrosis and grade of inflammation [ 1 , 2 ]. Liver biopsies are an invasive examination with possible traumatic complications including bleeding, pain, and pneumothorax and, therefore, these methods cannot be frequently repeated and not suitable for dynamic surveillance of the pathological changes of hepatic tissues [ 3 – 5 ]. Recently, several noninvasive diagnostic models of liver fibrosis have been established using combinations of serological markers, such as the aspartate transaminase and platelet ratio index (APRI), Hepascore, Fibroindex, slower lung function growth (SLFG), Fibroscan, Fibrotouch, and Forn's index [ 6 – 18 ].…”