Transient effects of 80 Hz stimulation on gait in STN DBS treated PD patients: A 15 months follow-up study

Effects of deep brain stimulation of the subthalamic nucleus on freezing of gait in Parkinson's disease: a prospective controlled study

“…This result is interesting in the light of recent studies that suggest controversial results on lowering the stimulation frequency to specifically target axial symptoms and FOG in the short and/or long term 8–10 26 27…”

Improving outcomes of subthalamic nucleus deep brain stimulation in Parkinson’s disease

“…In particular, short pulse widths decrease the activation of surrounding fibers as a result of specific axon properties such as chronaxie. Recently, an increasing number of reports have explored the use of low-frequency stimulation (60-80 Hz) to improve axial symptoms including freezing of gait, postural control, dysarthria, swallowing function and also bradykinesia [50,[52][53][54][55]. However, these reports only addressed the short-term effects, and the initial promising results were limited either by the transient clinical benefits or worsening of appendicular symptoms [52,56].…”

Low-frequency Versus High-frequency Subthalamic Nucleus Deep Brain Stimulation on Postural Control and Gait in Parkinson's Disease: A Quantitative Study

“…Some authors have reported a decrease in number of freezing episodes at 60 Hz of stimulation with no improvement in gait performance, as measured subjectively using a Stand-Walk-Sit test [23,24]. Using the same test, Ricchi et al (2012) showed that 80 Hz stimulation produced immediate improvements in gait, though the improvements were not sustained [25]. From the aforementioned studies, stimulating a low frequency seems to help persons with PD who presented gait-related impairments after having a high-frequency STN-DBS procedure.…”