Transient Cortical Blindness and Bioccipital Brain Lesions in Two Patients with Acute Intermittent Porphyria

Reversible posterior leukoencephalopathy syndrome complicating cytotoxic chemotherapy for hematologic malignancies

“…Many other associations have been reported, including microangiopathy [2], sickle cell disease [10], intravenous immunoglobulin use [28], large-volume red cell transfusion [16], stem cell re-infusion [12], use of erythropoietin or G-CSF [5,17], hypercalcemia [18], and acute intermittent porphyria [19,26].…”

“…Hypertension is also a feature in the vast majority of RPLS reported [5,7,[9][10][11][13][14][15][16]19,21,[23][24][25][26]. In contrast to encephalopathy caused by isolated malignant hypertension, patients with RPLS often present with only moderate levels of hypertension (systolic blood pressure 130-200 mmHg, diastolic blood pressure generally > 90 mmHg); in the majority of cases this still represents a significant increase above baseline levels.…”

A Case of posterior reversible encephalopathy syndrome in a pregnant woman with sickle cell anemia

“…15 All patients suffering from PRES have characteristic features of headache, altered levels of consciousness, visual changes and seizures. [16] Hypertension is a feature in the majority of RPLS patients, regardless of etiology 1,8,21,22,24,25 With blood pressure lowering, patients will often improve dramatically. Except in cases of malignant hypertension, patients with RPLS often present with only moderate levels of hypertension; in most of cases, however, this still represents a significant increase above baseline levels.…”

Reversible Posterior Encephalopathy Possibly Related to Coeliac Disease: A Vitamin-Depleted Brain?

“…PLES is also seen in normotensive patients treated with immunosuppressive drugs such as cyclosporin A, Tacrolimus and interferon alpha [1]and has been reported in patients with acute intermittent porphyria [6]and recently in a HIV-infected child [7]. …”